Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 2/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.38 |
| ▸ | ABCB1 | P08183 | 2/20 | 0.38 |
| ▸ | MAPT | P10636 | 3/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.38 |
| ▸ | HTR1A | P08908 | 1/20 | 0.37 |
| ▸ | HTR2B | P41595 | 1/20 | 0.37 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.36 |
| ▸ | GAA | P10253 | 2/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.35 |
| ▸ | MALT1 | Q9UDY8 | 1/20 | 0.34 |
| ▸ | KCNE1 | P15382 | 4/20 | 0.34 |
| ▸ | KCNQ1 | P51787 | 4/20 | 0.34 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6559904 | 0.88 | KCNE1 (0.39) | MEN1KMT2AABCB1MAPTALDH1A1 | |
| SCHEMBL6558631 | 0.81 | KCNE1 (0.46) | MEN1KMT2AMAPTALDH1A1HTT | |
| SCHEMBL6559337 | 0.81 | KCNE1 (0.47) | MEN1KMT2AALDH1A1LMNAKCNE1 | |
| SCHEMBL6559540 | 0.80 | KCNE1 (0.33) | MEN1KMT2AKCNE1KCNQ1 | |
| SCHEMBL6559266 | 0.78 | KCNE1 (0.52) | KCNE1KCNQ1 | |
| SCHEMBL6559417 | 0.78 | KCNE1 (0.37) | MEN1KMT2AKCNE1KCNQ1 | |
| SCHEMBL6559205 | 0.77 | SMN1; SMN2 (0.38) | MEN1KMT2AMAPTALDH1A1HTT | |
| Hydrochloric Acid SCHEMBL7830283 | 0.77 | KCNE1 (0.36) | MEN1KMT2AMAPTGAASMN1; SMN2 | |
| SCHEMBL6559889 | 0.75 | KCNE1 (0.54) | MEN1KMT2AABCB1KDM4ELMNA | |
| SCHEMBL6559994 | 0.75 | TLR3 (0.41) | MEN1KMT2AMAPTALDH1A1HTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0807629-B1 | Sulfonamido substituted chromane derivatives, method for their preparation, their use as medicaments or diagnostic agents aswell as medicaments containing them | AVENTIS PHARMA GMBH (DE) | 2004-03-03 | — | — | EP | disclosed |
| US-6191164-B1 | POTASSIUM CHANNEL MODULATORS; ANTIULCER AGENTS | HOECHST AKTIENGESELLSCHAFT (DE) | 2001-02-20 | — | — | US | disclosed |
| EP-0807629-A1 | Sulfonamido substituted chromane derivatives, method for their preparation, their use as medicaments or diagnostic agents aswell as medicaments containing them | HOECHST AKTIENGESELLSCHAFT (DE) | 1997-11-19 | — | — | EP | disclosed |