SCHEMBL6561138

SCHEMBL6561138

COc1cc(O)c(C(=O)c2cc(S(=O)(=O)O)ccc2O)cc1S(=O)(=O)O.[NaH]

nearest known ligand 0.64

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 4/20 0.64
LMNA P02545 3/20 0.64
MAPT P10636 2/20 0.64
KMT2A Q03164 1/20 0.64
HSD17B10 Q99714 5/20 0.49
KDM4E B2RXH2 3/20 0.49
HPGD P15428 3/20 0.49
PHLPP2 Q6ZVD8 1/20 0.44
CYP3A4 P08684 2/20 0.42
RECQL P46063 1/20 0.42
GAA P10253 2/20 0.39
HTT P42858 1/20 0.39
NPC1 O15118 1/20 0.38
RAB9A P51151 1/20 0.38
SLC22A6 Q4U2R8 1/20 0.38
SLC22A8 Q8TCC7 1/20 0.38
MPL P40238 1/20 0.38
CYP1A2 P05177 1/20 0.37
PGR P06401 1/20 0.37
ADORA3 P0DMS8 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6569641 0.89 LMNA (0.74) ALDH1A1LMNAMAPTKMT2AHSD17B10
SCHEMBL240881 0.89 LMNA (0.74) ALDH1A1LMNAMAPTKMT2AHSD17B10
SCHEMBL2583809 0.89 LMNA (0.74) ALDH1A1LMNAMAPTKMT2AHSD17B10
SCHEMBL240879 0.89 LMNA (0.74) ALDH1A1LMNAMAPTKMT2AHSD17B10
SCHEMBL30040274 0.87 LMNA (0.76) ALDH1A1LMNAMAPTKMT2AHSD17B10
SCHEMBL93914 0.87 LMNA (0.76) ALDH1A1LMNAMAPTKMT2AHSD17B10
SCHEMBL9774351 0.85 LMNA (0.74) ALDH1A1LMNAMAPTKMT2AHSD17B10
SCHEMBL1273925 0.84 LMNA (0.76) ALDH1A1LMNAMAPTKMT2AHSD17B10
SCHEMBL345162 0.82 MAPT (0.64) ALDH1A1LMNAMAPTKMT2AHSD17B10
SCHEMBL29967586 0.82 MAPT (0.64) ALDH1A1LMNAMAPTKMT2AHSD17B10

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1110971-B1 Propylene glycol hyaluronate and agent for external use to skin using the same KIBUN FOOD CHEMIFA (JP) 2004-08-11 EP disclosed
US-6723704-B2 FOR COSMETICS, DRUGS, MOISTURIZER KIBUN FOOD CHEMIFA CO., LTD. (JP) 2004-04-20 US disclosed
US-6710038-B1 VISCOSITY STABILITY AT LOW-PH KIBUN FOOD CHEMIFA CO., LTD. (JP) 2004-03-23 US disclosed
US-20040013627-A1 Propylene glycol hyaluronate esters and composition comprising the same KIBUN FOOD CHEMIFA CO., LTD (JP) 2004-01-22 US disclosed
EP-1167374-B1 Glycosphingolipid KIBUN FOOD CHEMIFA (JP) 2003-09-17 EP disclosed
US-20020037291-A1 Sphingoglycolipid KIBUN FOOD CHEMIFA CO., LTD. (JP) 2002-03-28 US disclosed
EP-1167374-A1 Glycosphingolipid Kibun Food ChemiFA Co., Ltd. (JP) 2002-01-02 EP disclosed
EP-1110971-A1 Propylene glycol hyaluronate and agent for external use to skin using the same Kibun Food ChemiFA Co., Ltd. (JP) 2001-06-27 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20020037291-A1 Sphingoglycolipid UGCG, ALG1, FUT6 ALDH1A1 2326/4885LMNA 4464/4885MAPT 4052/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.