SCHEMBL6561254

SCHEMBL6561254

C=CS(=O)(=O)c1ccc(N)c(S(=O)(=O)O)c1

nearest known ligand 0.43

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 5/20 0.43
HSD17B10 Q99714 4/20 0.43
MAPT P10636 3/20 0.43
TSHR P16473 3/20 0.43
RAB9A P51151 2/20 0.43
NPC1 O15118 1/20 0.43
LMNA P02545 1/20 0.43
TP53 P04637 1/20 0.43
XBP1 P17861 1/20 0.43
MAPK1 P28482 1/20 0.43
HTT P42858 1/20 0.43
MDM2 Q00987 1/20 0.43
SMN1; SMN2 Q16637 1/20 0.43
GAA P10253 2/20 0.42
KDM4E B2RXH2 1/20 0.42
MEN1 O00255 1/20 0.42
PKM P14618 1/20 0.42
KMT2A Q03164 1/20 0.42
CYP2C9 P11712 1/20 0.41
CYP2C19 P33261 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9558890 0.89 ALDH1A1 (0.46) ALDH1A1HSD17B10MAPTTSHRRAB9A
SCHEMBL9336200 0.86 ALDH1A1 (0.46) ALDH1A1HSD17B10MAPTTSHRRAB9A
SCHEMBL7712980 0.84 SENP2 (0.53) ALDH1A1HSD17B10MAPTMEN1KMT2A
SCHEMBL7712976 0.84 SENP2 (0.53) ALDH1A1HSD17B10MAPTMEN1KMT2A
SCHEMBL142003 0.83 ALDH1A1 (0.59) ALDH1A1HSD17B10MAPTTSHRRAB9A
SCHEMBL153646 0.83 ALDH1A1 (0.59) ALDH1A1HSD17B10MAPTTSHRRAB9A
SCHEMBL142001 0.81 ALDH1A1 (0.57) ALDH1A1HSD17B10MAPTTSHRRAB9A
SCHEMBL7064778 0.81 ALDH1A1 (0.57) ALDH1A1HSD17B10MAPTTSHRRAB9A
Hydrochloric Acid SCHEMBL28203178 0.81 ALDH1A1 (0.57) ALDH1A1HSD17B10MAPTTSHRRAB9A
SCHEMBL1376733 0.81 GAA (0.53) ALDH1A1HSD17B10MAPTTSHRRAB9A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 122 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1055710-B1 Water-soluble fibre-reactive dyestuffs, process for their preparation and their use DYSTAR TEXTILFARBEN GMBH & CO (DE) 2004-08-11 EP disclosed
US-6444794-B1 COMPLEXING WITH SUBSTRATE DYSTAR TEXTILFARBEN GMBH & CO. DEUTSCHLAND KG (DE) 2002-09-03 US disclosed
US-6376656-B1 DISAZO DYES, TRIAZINE DYES DYSTAR TEXTILFARBEN GMBH & CO. DEUTSCHLAND KG (DE) 2002-04-23 US disclosed
EP-1055710-A1 Water-soluble fibre-reactive dyestuffs, process for their preparation and their use DyStar Textilfarben GmbH & Co. Deutschland KG (DE) 2000-11-29 EP disclosed
EP-0703906-B1 FIBER REACTIVE ANTHRAQUINONE DYES DYSTAR L P (US) 2000-08-30 EP disclosed
EP-0652262-B1 Reactive dyestuffs, their preparation and use BAYER AG (DE) 2000-07-12 EP disclosed
EP-0838504-B1 Water-soluble fiber-reactive dyes, process for their preparation and the use thereof DYSTAR TEXTILFARBEN GMBH & CO (DE) 2000-06-07 EP disclosed
US-6060591-A FOR DYEING A MATERIAL CONTAINING HYDROXY OR CARBOXAMIDE GROUPS OR BOTH DY STAR TEXTILFARBEN GMBH & CO. DEUTSCHLAND K.G. (DE) 2000-05-09 US disclosed
US-6025478-A HIGH REACTIVITY AND FIXING CAPACITY, GOOD LOW TEMPERATURE DYEING, GOOD COLOR INTENSITY, LIGHTFASTNESS, WASHFASTNESS BAYER AG (DE) 2000-02-15 US disclosed
US-6015885-A COLOR-STABLE, WATERPROOF DYES FOR NATURAL FIBERS OR REGENERATED CELLULOSE SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2000-01-18 US disclosed
EP-0198350-A1 Reactive disazo dyes BAYER AG (DE) 1986-10-22 EP disclosed
EP-0177445-A1 Reactive dyes, their preparation and their use CIBA-GEIGY AG (CH) 1986-04-09 EP disclosed
EP-0174275-A1 Process for dyeing or printing fibrous textile materials with reactive dyes CIBA-GEIGY AG (CH) 1986-03-12 EP disclosed
EP-0167490-A1 Reactive dyestuffs, their preparation and their use CIBA-GEIGY AG (CH) 1986-01-08 EP disclosed
EP-0149170-A2 Reactive dyes, their preparation and their use CIBA-GEIGY AG (CH) 1985-07-24 EP disclosed
EP-0141776-A1 Reactive dyes, their preparation and their use CIBA-GEIGY AG (CH) 1985-05-15 EP disclosed
EP-0134193-A1 Reactive dyes, their preparation and their use CIBA-GEIGY AG (CH) 1985-03-13 EP disclosed
EP-0133843-A1 Reactive dyes, their preparation and their use CIBA-GEIGY AG (CH) 1985-03-06 EP disclosed
EP-0040806-B1 WATER-SOLUBLE, COLOURED COMPOUNDS, PROCESS FOR THEIR PREPARATION AND THEIR USE AS DYESTUFFS HOECHST AKTIENGESELLSCHAFT (DE) 1984-09-19 EP disclosed
EP-0040806-A2 Water-soluble, coloured compounds, process for their preparation and their use as dyestuffs HOECHST AKTIENGESELLSCHAFT (DE) 1981-12-02 EP disclosed