SCHEMBL7712976

SCHEMBL7712976

C=CS(=O)(=O)c1ccc(/N=N/c2ccc(N)c(S(=O)(=O)O)c2)c(S(=O)(=O)O)c1

nearest known ligand 0.53

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
SENP2 Q9HC62 9/20 0.53
SENP1 Q9P0U3 8/20 0.53
SENP3 Q9H4L4 7/20 0.53
SUMO2 P61956 5/20 0.53
SUMO1 P63165 5/20 0.53
SENP7 Q9BQF6 5/20 0.53
ENPP2 Q13822 1/20 0.43
CYP2C9 P11712 1/20 0.42
CYP2C19 P33261 1/20 0.42
HSD17B10 Q99714 1/20 0.42
PHLPP2 Q6ZVD8 3/20 0.41
CD40 P25942 1/20 0.40
CD40LG P29965 1/20 0.40
PRMT1 Q99873 1/20 0.39
GLO1 Q04760 3/20 0.39
MEN1 O00255 1/20 0.38
ALDH1A1 P00352 1/20 0.38
APP P05067 1/20 0.38
MAPT P10636 1/20 0.38
THRB P10828 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7712980 1.00 SENP2 (0.53) SENP2SENP1SENP3SUMO2SUMO1
SCHEMBL6561254 0.84 ALDH1A1 (0.43) SENP2SENP1SENP3SUMO2SUMO1
SCHEMBL12053188 0.81 ENPP2 (0.45) SENP2SENP1SENP3SUMO2SUMO1
SCHEMBL31099405 0.78 SENP2 (0.60) SENP2SENP1SENP3SUMO2SUMO1
SCHEMBL110924 0.78 SENP2 (0.60) SENP2SENP1SENP3SUMO2SUMO1
SCHEMBL1436156 0.78 SENP2 (0.60) SENP2SENP1SENP3SUMO2SUMO1
SCHEMBL110923 0.78 SENP2 (0.60) SENP2SENP1SENP3SUMO2SUMO1
SCHEMBL11235121 0.77 SENP2 (0.57) SENP2SENP1SENP3SUMO2SUMO1
SCHEMBL1712890 0.77 SENP2 (0.58) SENP2SENP1SENP3SUMO2SUMO1
SCHEMBL1436155 0.77 SENP2 (0.59) SENP2SENP1SENP3SUMO2SUMO1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6376656-B1 DISAZO DYES, TRIAZINE DYES DYSTAR TEXTILFARBEN GMBH & CO. DEUTSCHLAND KG (DE) 2002-04-23 US disclosed
US-6025478-A HIGH REACTIVITY AND FIXING CAPACITY, GOOD LOW TEMPERATURE DYEING, GOOD COLOR INTENSITY, LIGHTFASTNESS, WASHFASTNESS BAYER AG (DE) 2000-02-15 US disclosed
US-5686642-A Compounds useful for the preparation of bi-and polyfunctional reactive dyestuffs BAYER AKTIENGESELLSCHAFT (DE) 1997-11-11 US disclosed
US-5597902-A MONOAZO DYES, DISAZO DYES, NAPHTHOL DYES AND TRIAZO DYES FOR SILK, WOOL, LEATHER AND POLYAMIDES OR CELLULOSE BAYER AKTIENGESELLSCHAFT (DE) 1997-01-28 US disclosed
US-5502174-A Reactive dyestuffs based on a substituted barbituric acid BAYER AKTIENGESELLSCHAFT (DE) 1996-03-26 US disclosed
US-5093484-A Water soluble; colorfast shades on cotton BAYER AKTIENGESELLSCHAFT (DE) 1992-03-03 US disclosed