Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR7 | P34969 | 3/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.47 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.45 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.45 |
| ▸ | DRD2 | P14416 | 1/20 | 0.44 |
| ▸ | DRD1 | P21728 | 1/20 | 0.44 |
| ▸ | DRD4 | P21917 | 1/20 | 0.44 |
| ▸ | DRD5 | P21918 | 1/20 | 0.44 |
| ▸ | HTR1B | P28222 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | LTA4H | P09960 | 1/20 | 0.38 |
| ▸ | LSS | P48449 | 1/20 | 0.38 |
| ▸ | HRH1 | P35367 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6560797 | 0.79 | AVPR2 (0.48) | ALDH1A1KDM4ESMN1; SMN2LMNAPOLB | |
| SCHEMBL6561450 | 0.78 | HTR7 (0.50) | HTR7ALDH1A1KDM4ESMN1; SMN2ADRB2 | |
| SCHEMBL7946819 | 0.77 | HTR7 (0.52) | HTR7ALDH1A1KDM4ESMN1; SMN2ADRB2 | |
| SCHEMBL6563153 | 0.77 | HTR7 (0.56) | HTR7ALDH1A1KDM4ESMN1; SMN2ADRB2 | |
| SCHEMBL6560069 | 0.74 | HTR7 (0.55) | HTR7ALDH1A1KDM4ESMN1; SMN2ADRB2 | |
| SCHEMBL28238357 | 0.71 | ALDH1A1 (0.42) | ALDH1A1LMNAPOLBMAPTTSHR | |
| SCHEMBL7805578 | 0.71 | HTR7 (0.48) | HTR7ALDH1A1KDM4ESMN1; SMN2ADRB2 | |
| SCHEMBL7949144 | 0.70 | HTR7 (0.60) | HTR7ALDH1A1KDM4ESMN1; SMN2ADRB2 | |
| SCHEMBL29904797 | 0.70 | HTR7 (1.00) | HTR7ALDH1A1KDM4ESMN1; SMN2ADRB2 | |
| SCHEMBL6669515 | 0.68 | HTR7 (0.67) | HTR7ALDH1A1KDM4ESMN1; SMN2ADRB2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1071670-B1 | NOVEL DIPHENYL-SUBSTITUTED 5-RING-HETEROCYCLES, METHOD FOR PRODUCING THEM AND THEIR USE AS MEDICAMENTS | BOEHRINGER INGELHEIM PHARMA (DE) | 2004-07-07 | — | — | EP | disclosed |
| US-6255327-B1 | ANTIHYPOXC, ANTIISCHEMIC AGENTS | BOEHRINGER INGELHEIM PHARMA KG (DE) | 2001-07-03 | — | — | US | disclosed |