Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR7 | P34969 | 3/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.45 |
| ▸ | HTR1B | P28222 | 1/20 | 0.44 |
| ▸ | ADRB2 | P07550 | 2/20 | 0.43 |
| ▸ | ADRB1 | P08588 | 2/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | POLB | P06746 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
| ▸ | TSHR | P16473 | 1/20 | 0.42 |
| ▸ | HTT | P42858 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | DRD2 | P14416 | 1/20 | 0.42 |
| ▸ | DRD1 | P21728 | 1/20 | 0.42 |
| ▸ | DRD4 | P21917 | 1/20 | 0.42 |
| ▸ | DRD5 | P21918 | 1/20 | 0.42 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.38 |
| ▸ | AVPR2 | P30518 | 2/20 | 0.38 |
| ▸ | AVPR1A | P37288 | 2/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6561418 | 0.81 | BRD4 (0.49) | ALDH1A1SMN1; SMN2LMNAMAPTTSHR | |
| SCHEMBL6559765 | 0.78 | HTR7 (0.53) | HTR7ALDH1A1KDM4ESMN1; SMN2HTR1B | |
| SCHEMBL6561335 | 0.78 | HTR7 (0.52) | HTR7ALDH1A1KDM4ESMN1; SMN2HTR1B | |
| SCHEMBL7803874 | 0.76 | ADORA1 (0.36) | SMN1; SMN2MAPTTSHRADORA1AVPR2 | |
| SCHEMBL7949144 | 0.76 | HTR7 (0.60) | HTR7ALDH1A1KDM4ESMN1; SMN2HTR1B | |
| SCHEMBL7805578 | 0.74 | HTR7 (0.48) | HTR7ALDH1A1KDM4ESMN1; SMN2HTR1B | |
| SCHEMBL14118409 | 0.72 | ALDH1A1 (0.50) | ALDH1A1LMNAPOLBMAPTTSHR | |
| SCHEMBL6559724 | 0.70 | GAA (0.47) | ALDH1A1KDM4EPOLBMAPTADORA1 | |
| SCHEMBL7946819 | 0.70 | HTR7 (0.52) | HTR7ALDH1A1KDM4ESMN1; SMN2HTR1B | |
| SCHEMBL6669515 | 0.69 | HTR7 (0.67) | HTR7ALDH1A1KDM4ESMN1; SMN2HTR1B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1071670-B1 | NOVEL DIPHENYL-SUBSTITUTED 5-RING-HETEROCYCLES, METHOD FOR PRODUCING THEM AND THEIR USE AS MEDICAMENTS | BOEHRINGER INGELHEIM PHARMA (DE) | 2004-07-07 | — | — | EP | disclosed |
| US-6255327-B1 | ANTIHYPOXC, ANTIISCHEMIC AGENTS | BOEHRINGER INGELHEIM PHARMA KG (DE) | 2001-07-03 | — | — | US | disclosed |