Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | THRB | P10828 | 1/20 | 0.50 |
| ▸ | TSHR | P16473 | 5/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
| ▸ | HPGD | P15428 | 4/20 | 0.35 |
| ▸ | RAB9A | P51151 | 2/20 | 0.35 |
| ▸ | NPC1 | O15118 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.34 |
| ▸ | CES2 | O00748 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
| ▸ | TP53 | P04637 | 1/20 | 0.34 |
| ▸ | GAA | P10253 | 1/20 | 0.34 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL251951 | 0.81 | ALDH1A1 (0.60) | TSHRALDH1A1L3MBTL1HPGDLMNA | |
| SCHEMBL28996313 | 0.80 | TSHR (0.44) | THRBTSHRALDH1A1KMT2AHSD17B10 | |
| SCHEMBL234130 | 0.80 | THRB (0.78) | THRBTSHRALDH1A1KMT2AL3MBTL1 | |
| SCHEMBL28996282 | 0.80 | TSHR (0.44) | THRBTSHRALDH1A1KMT2AHSD17B10 | |
| SCHEMBL9056348 | 0.79 | TSHR (0.62) | TSHRALDH1A1LMNACES2TP53 | |
| SCHEMBL151561 | 0.79 | ALDH1A1 (0.74) | THRBTSHRALDH1A1KMT2AL3MBTL1 | |
| SCHEMBL253034 | 0.78 | THRB (0.48) | THRBTSHRALDH1A1KMT2AL3MBTL1 | |
| SCHEMBL5888797 | 0.78 | TSHR (0.37) | THRBTSHRALDH1A1SMN1; SMN2 | |
| SCHEMBL21599119 | 0.78 | TSHR (0.66) | TSHRALDH1A1LMNACES2 | |
| SCHEMBL11755056 | 0.78 | TSHR (0.66) | TSHRALDH1A1LMNACES2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1398831-A2 | Air gaps formation | Shipley Co. L.L.C. (US) | 2004-03-17 | — | — | EP | disclosed |