SCHEMBL253034

SCHEMBL253034

CC=C(C)C(=O)OCCCOCC

nearest known ligand 0.48

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
THRB P10828 1/20 0.48
TSHR P16473 5/20 0.45
ALDH1A1 P00352 4/20 0.45
ATM Q13315 1/20 0.35
GLO1 Q04760 1/20 0.34
HPGD P15428 3/20 0.34
NPC1 O15118 1/20 0.34
RAB9A P51151 1/20 0.34
CES2 O00748 1/20 0.33
LMNA P02545 1/20 0.33
HSD17B10 Q99714 1/20 0.33
HTT P42858 1/20 0.33
KMT2A Q03164 1/20 0.32
L3MBTL1 Q9Y468 1/20 0.32
HCAR2 Q8TDS4 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9701061 0.88 THRB (0.62) THRBTSHRALDH1A1GLO1HPGD
SCHEMBL15302627 0.86 THRB (0.60) THRBTSHRALDH1A1GLO1HPGD
SCHEMBL3768916 0.86 THRB (0.60) THRBTSHRALDH1A1GLO1HPGD
SCHEMBL2352262 0.85 THRB (0.46) THRBTSHRALDH1A1ATMGLO1
SCHEMBL3748655 0.83 TSHR (0.47) THRBTSHRALDH1A1ATMHPGD
SCHEMBL10456655 0.83 TSHR (0.47) THRBTSHRALDH1A1ATMHPGD
SCHEMBL721147 0.82 ALDH1A1 (0.58) TSHRALDH1A1ATMHPGDRAB9A
SCHEMBL873334 0.82 ALDH1A1 (0.58) TSHRALDH1A1ATMHPGDRAB9A
SCHEMBL262657 0.82 ALDH1A1 (0.58) TSHRALDH1A1ATMHPGDRAB9A
SCHEMBL21081969 0.81 MEN1 (0.41) THRBTSHRALDH1A1HSD17B10HTT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 44 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2968090-B1 METHOD OF REMOVING POLYMERIZED COATINGS FROM HUMAN NAILS, POLYMERIZED COATING FOR HUMAN NAILS HAVING IMPROVED REMOVABILITY, AND TWO PACKAGE SYSTEM MYCONE DENTAL SUPPLY COMPANY INC (US) 2021-06-02 EP disclosed
EP-2525773-B1 EASILY APPLIABLE, STORAGE STABLE, RADIATION-CURABLE, PIGMENTED, ARTIFICIAL NAIL GEL COATINGS MYCONE DENTAL SUPPLY CO INC (US) 2020-02-12 EP disclosed
EP-2547730-B1 METHOD OF PREPARATION OF RADIATION-CURABLE COLORED ARTIFICIAL NAIL GELS MYCONE DENTAL SUPPLY COMPANY INC (US) 2019-07-10 EP disclosed
US-20190151223-A1 ONE PART ARTIFICIAL NAIL COMPOSITIONS MYCONE DENTAL SUPPLY CO INC (US) 2019-05-23 US disclosed
US-20190151222-A1 ONE PART ARTIFICIAL NAIL SCULPTING COMPOSITIONS AND METHODS WITHOUT REACTIVE OLIGOMERS NAIL ALLIANCE, LLC 2019-05-23 US disclosed
US-20190125652-A1 One Part Acrylic Nail Formulation MYCONE DENTAL SUPPLY CO INC (US) 2019-05-02 US disclosed
EP-3471831-A1 ONE PART ACRYLIC NAIL FORMULATION Mycone Dental Supply Company, Inc. (US) 2019-04-24 EP disclosed
EP-2363109-B1 Uv-curable nail coating formulations based on renewable polyols MYCONE DENTAL SUPPLY COMPANY INC (US) 2018-09-05 EP disclosed
US-20180092827-A1 ONE PART ACRYLIC NAIL FORMULATION WITH DISCONTINUOUS PHASE MYCONE DENTAL SUPPLY CO INC (US) 2018-04-05 US disclosed
US-9931284-B2 Method of removing polymerized coatings for human nails, polymerized coating for human nails having improved removability, and two package system MYCONE DENTAL SUPPLY COMPANY, INC. (US) 2018-04-03 US disclosed
EP-2547730-A2 METHOD OF PREPARATION OF RADIATION-CURABLE COLORED ARTIFICIAL NAIL GELS Mycone Dental Supply Company Inc. (US) 2013-01-23 EP disclosed
US-20120252710-A1 METHOD AND COMPOSITION FOR REMOVING RADIATION-CURABLE, PIGMENTED, ARTIFICIAL NAIL GEL COATINGS MYCONE DENTAL SUPPLY CO., INC. (US) 2012-10-04 US disclosed
US-20120004340-A1 METHOD OF PREPARATION OF RADIATION-CURABLE COLORED ARTIFICIAL NAIL GELS MYCONE DENTAL SUPPLY COMPANY, INC. (US) 2012-01-05 US disclosed
WO-2011130362-A2 EASILY APPLIABLE, STORAGE STABLE, RADIATION-CURABLE, PIGMENTED, ARTIFICIAL NAIL GEL COATINGS MYCONE DENTAL SUPPLY CO., INC. (US) 2011-10-20 WO disclosed
US-20110256079-A1 Easily appliable, storage stable, radiation-curable, pigmented, artificial nail gel coatings MYCONE DENTAL CORPORATION 2011-10-20 US disclosed
US-20110256080-A1 Easily appliable, storage stable, radiation-curable, pigmented, artificial nail gel coatings MYCONE DENTAL CORPORATION 2011-10-20 US disclosed
WO-2011115795-A2 METHOD OF PREPARATION OF RADIATION-CURABLE COLORED ARTIFICIAL NAIL GELS MYCONE DENTAL SUPPLY COMPANY, INC. (US) 2011-09-22 WO disclosed
US-20110226271-A1 Method of Preparation of Radiation-Curable Colored Artificial Nail Gels MYCONE DENTAL SUPPLY COMPANY, INC. (US) 2011-09-22 US disclosed
EP-2363109-A2 Uv-curable nail coating formulations based on renewable polyols Mycone Dental Supply Company, Inc. (US) 2011-09-07 EP disclosed
US-20110182837-A1 UV-CURABLE NAIL COATING FORMULATIONS BASED ON RENEWABLE POLYOLS MYCONE DENTAL SUPPLY CO., INC. (US) 2011-07-28 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20190151223-A1 ONE PART ARTIFICIAL NAIL COMPOSITIONS POLR1C, PIK3C3, NACA THRB 1902/4885TSHR 1716/4885ALDH1A1 3782/4885
US-20190151222-A1 ONE PART ARTIFICIAL NAIL SCULPTING COMPOSITIONS AND METHODS WITHOUT REACTIVE OLIGOMERS POLR1C, NACA, SUCLG1 THRB 732/4885TSHR 1396/4885ALDH1A1 2608/4885
US-20180092827-A1 ONE PART ACRYLIC NAIL FORMULATION WITH DISCONTINUOUS PHASE POLR1C, NACA, PIK3C3 THRB 853/4885TSHR 1748/4885ALDH1A1 2055/4885
US-20190125652-A1 One Part Acrylic Nail Formulation POLR1C, NACA, PIK3C3 THRB 2500/4885TSHR 3359/4885ALDH1A1 321/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.