⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL221825 | 0.75 | SLC9A1 (0.41) | — | |
| SCHEMBL20014008 | 0.72 | — | — | |
| SCHEMBL16652006 | 0.69 | ADORA2A (0.36) | — | |
| SCHEMBL2078821 | 0.69 | ADORA2A (0.36) | — | |
| SCHEMBL11480635 | 0.69 | ADORA2A (0.36) | — | |
| SCHEMBL25979874 | 0.69 | ADORA2A (0.36) | — | |
| SCHEMBL9770361 | 0.68 | — | — | |
| SCHEMBL19243050 | 0.67 | NOTUM (0.40) | — | |
| SCHEMBL19586641 | 0.67 | — | — | |
| SCHEMBL13469216 | 0.67 | ADORA2A (0.35) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 41 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021163727-A1 | PIKFYVE KINASE INHIBITORS | AcuraStem Incorporated (US) | 2021-08-19 | — | — | WO | disclosed |
| WO-2021032209-A1 | ANTI-INFLUENZA VIRUS COMPOUND, PREPARATION METHOD AND USE THEREOF | 四川海思科制药有限公司 | 2021-02-25 | — | — | WO | disclosed |
| EP-3092227-B1 | BICYCLIC HETEROCYCLIC DERIVATIVES AS BROMODOMAIN INHIBITORS | ORION CORP (FI) | 2018-07-11 | — | — | EP | disclosed |
| US-20170143708-A1 | COMPOUNDS, COMPOSITIONS AND METHODS OF AGELASTATIN ALKALOIDS | MASSACHUSETTS INSTITUTE OF TECHNOLOGY (US) | 2017-05-25 | — | — | US | disclosed |
| US-9527828-B2 | Method for expanding hematopoietic stem cells using heterocyclic compound | NISSAN CHEMICAL INDUSTRIES, LTD. (JP) | 2016-12-27 | — | — | US | disclosed |
| US-9527828-B2 | Method for expanding hematopoietic stem cells using heterocyclic compound | NISSAN CHEMICAL INDUSTRIES, LTD. (JP) | 2016-12-27 | — | — | US | disclosed |
| US-20160368906-A1 | BICYCLIC HETEROCYCLIC DERIVATIVES AS BROMODOMAIN INHIBITORS | ORION CORPORATION (FI) | 2016-12-22 | — | — | US | disclosed |
| EP-2218716-B1 | METHOD FOR AMPLIFYING HEMATOPOIETIC STEM CELLS USING HETEROCYCLIC COMPOUND | NISSAN CHEMICAL IND LTD (JP) | 2016-11-16 | — | — | EP | disclosed |
| US-9328085-B2 | Heterocyclic compounds and expansion agents for hematopoietic stem cells | NISSAN CHEMICAL INDUSTRIES, LTD. (JP) | 2016-05-03 | — | — | US | disclosed |
| US-9328085-B2 | Heterocyclic compounds and expansion agents for hematopoietic stem cells | NISSAN CHEMICAL INDUSTRIES, LTD. (JP) | 2016-05-03 | — | — | US | disclosed |
| US-20080312270-A1 | COMPOUNDS AND METHODS USEFUL FOR TREATING ASTHMA AND ALLERGIC INFLAMMATION | AMGEN INC. | 2008-12-18 | — | — | US | disclosed |
| WO-2008137027-A2 | COMPOUNDS AS CRTH2 AND/OR PGD2 RECEPTORS MODULATORS AND THEIR USE FOR TREATING ASTHMA AND ALLERGIC INFLAMMATION | AMGEN INC. (US) | 2008-11-13 | — | — | WO | disclosed |
| US-20070161681-A1 | ETHER DERIVATIVES USEFUL AS INHIBITORS OF PDE4 ISOZYMES | PFIZER INC. (US) | 2007-07-12 | — | — | US | disclosed |
| US-7183293-B2 | Ether derivatives useful as inhibitors of PDE4 isozymes | PFIZER INC. (US) | 2007-02-27 | — | — | US | disclosed |
| EP-0978546-B1 | Ink compositions containing an ammonium carboxylate salt | HEWLETT PACKARD CO (US) | 2004-03-24 | — | — | EP | disclosed |
| EP-0978546-A1 | Ink compositions containing an ammonium carboxylate salt | Hewlett-Packard Company (US) | 2000-02-09 | — | — | EP | disclosed |
| US-5925176-A | INK COMPRISING AMMONIUM CARBOXYLATE SALT AND SURFACTANT; PREVENTS THERMALLY INDUCED PHASE SEPARATION | HEWLETT-PACKARD COMPANY (US) | 1999-07-20 | — | — | US | disclosed |
| EP-0544487-B1 | Anti-coalescent ink composition and method for making the same | HEWLETT PACKARD CO (US) | 1996-07-03 | — | — | EP | disclosed |
| EP-0544487-A1 | Anti-coalescent ink composition and method for making the same | Hewlett-Packard Company (US) | 1993-06-02 | — | — | EP | disclosed |
| US-5188664-A | Combining chemical dye with polyether polyol to reduce surface tension and to increase drip mass per firing | HEWLETT-PACKARD COMPANY (US) | 1993-02-23 | — | — | US | disclosed |