Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADORA2A | P29274 | 2/20 | 0.36 |
| ▸ | ADORA2B | P29275 | 2/20 | 0.36 |
| ▸ | GRIA1 | P42261 | 1/20 | 0.36 |
| ▸ | GRIA2 | P42262 | 1/20 | 0.36 |
| ▸ | GRIA3 | P42263 | 1/20 | 0.36 |
| ▸ | GRIA4 | P48058 | 1/20 | 0.36 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.34 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.34 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 3/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.33 |
| ▸ | SIRT2 | Q8IXJ6 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 2/20 | 0.32 |
| ▸ | MAPT | P10636 | 2/20 | 0.32 |
| ▸ | PABPC1 | P11940 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.32 |
| ▸ | TSHR | P16473 | 1/20 | 0.32 |
| ▸ | BLM | P54132 | 1/20 | 0.32 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| 5-Bromouracil SCHEMBL28330235 | 0.80 | ATAD2 (0.36) | GRIA1GRIA2GRIA3GRIA4LMNA | |
| SCHEMBL221825 | 0.74 | SLC9A1 (0.41) | ADORA2AADORA2BADRA1AADORA3ADORA1 | |
| SCHEMBL28328175 | 0.74 | ADORA2A (0.47) | ADORA2AADORA2BADRA1AADORA3ADORA1 | |
| SCHEMBL2078821 | 0.73 | ADORA2A (0.36) | ADORA2AADORA2BADORA3ADORA1LMNA | |
| SCHEMBL16652006 | 0.73 | ADORA2A (0.36) | ADORA2AADORA2BADORA3ADORA1LMNA | |
| SCHEMBL11480635 | 0.73 | ADORA2A (0.36) | ADORA2AADORA2BADORA3ADORA1LMNA | |
| SCHEMBL11716358 | 0.72 | ALDH1A1 (0.39) | ADORA2BADRA1AMAPTALDH1A1CYP3A4 | |
| SCHEMBL7951152 | 0.72 | ADORA2A (0.33) | ADORA2AADORA2BADORA3ADORA1LMNA | |
| SCHEMBL27989701 | 0.72 | CYP1A2 (0.51) | ADORA2AADORA2BGRIA1GRIA2GRIA3 | |
| SCHEMBL13469216 | 0.71 | ADORA2A (0.35) | ADORA2AADORA2BADRA1AADORA3ADORA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 57 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-110156750-A | Pyrimidine ring14The preparation method of the amber love song Ge Lieting of C flag | 无锡贝塔医药科技有限公司 | 2019-08-23 | — | — | CN | claimed |
| CN-109734673-A | A kind of purification process of compound | 浙江华贝药业有限责任公司 | 2019-05-10 | — | — | CN | claimed |
| CN-106336396-B | A kind of preparation method of alogliptin benzoate | 合肥立方制药股份有限公司 | 2019-04-09 | — | — | CN | claimed |
| CN-109020900-A | The preparation method of the chloro- 3- methyluracil of 6- | 浙江先锋科技股份有限公司 | 2018-12-18 | — | — | CN | claimed |
| CN-108822080-A | The preparation method of amber love song Ge Lieting | 四川新斯顿制药股份有限公司 | 2018-11-16 | — | — | CN | claimed |
| CN-108586360-A | A kind of preparation method of the chloro- 3- methyluracils of 6- | 峨眉山宏昇药业股份有限公司 | 2018-09-28 | — | — | CN | claimed |
| CN-105541793-B | The synthetic method of bent Ge Lieting | 河北国龙制药有限公司 | 2018-08-10 | — | — | CN | claimed |
| CN-207435359-U | A kind of chloro- 3- methyluracils process units of 6- | 杭州布朗生物医药科技有限公司 | 2018-06-01 | — | — | CN | claimed |
| CN-107540656-A | A kind of preparation method of SYR-322 | 常州市第四制药厂有限公司 | 2018-01-05 | — | — | CN | claimed |
| CN-106632241-A | Preparation method of trelagliptin succinate | 安徽省金楠医疗科技有限公司 | 2017-05-10 | — | — | CN | claimed |
| CN-106279104-A | A kind of process modification method preparing succinum love song Ge Lieting | 杭州新博思生物医药有限公司 | 2017-01-04 | — | — | CN | claimed |
| CN-105646447-A | Synthesis method of dipeptidyl peptidase inhibitor | 北京康立生医药技术开发有限公司 | 2016-06-08 | — | — | CN | claimed |
| CN-103012287-B | Preparation method of 6-chlorine-3-methyl uracil | HEALTANG BIOTECH CO LTD | 2015-06-17 | — | — | CN | claimed |
| WO-2023150592-A2 | N3-SUBSTITUTED URACIL COMPOUNDS AS TRPA1 INHIBITORS | D.E. SHAW RESEARCH, LLC (US) | 2023-08-10 | — | — | WO | disclosed |
| CN-111693627-B | Detection method and application of 6-chloro-3-methyl uracil and related substances thereof | 山西振东制药股份有限公司 | 2022-05-13 | — | — | CN | disclosed |
| CN-113939599-A | Hybrid all-LNA oligonucleotides | 豪夫迈·罗氏有限公司 | 2022-01-14 | — | — | CN | disclosed |
| CN-104086527-B | A kind of synthetic method of SYR-322 | 湖南欧亚生物有限公司 | 2016-09-21 | — | — | CN | disclosed |
| CN-104193726-B | A kind of synthetic method of SYR-322 | 江苏德源药业股份有限公司 | 2016-08-24 | — | — | CN | disclosed |
| CN-105646447-A | Synthesis method of dipeptidyl peptidase inhibitor | 北京康立生医药技术开发有限公司 | 2016-06-08 | — | — | CN | disclosed |
| CN-103012287-B | Preparation method of 6-chlorine-3-methyl uracil | HEALTANG BIOTECH CO LTD | 2015-06-17 | — | — | CN | disclosed |