Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.45 |
| ▸ | LDHA | P00338 | 1/20 | 0.44 |
| ▸ | GAA | P10253 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
| ▸ | RAB9A | P51151 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
| ▸ | ATM | Q13315 | 1/20 | 0.41 |
| ▸ | EGFR | P00533 | 1/20 | 0.40 |
| ▸ | CFTR | P13569 | 1/20 | 0.39 |
| ▸ | GOPC | Q9HD26 | 1/20 | 0.39 |
| ▸ | EPHX2 | P34913 | 2/20 | 0.37 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.37 |
| ▸ | ADRA1D | P25100 | 2/20 | 0.37 |
| ▸ | ADRA1A | P35348 | 2/20 | 0.37 |
| ▸ | ADRA1B | P35368 | 2/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.36 |
| ▸ | AR | P10275 | 1/20 | 0.36 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.36 |
| ▸ | MAOB | P27338 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29258996 | 1.00 | SIGMAR1 (0.45) | SIGMAR1LDHAGAAMAPTRAB9A | |
| SCHEMBL27794644 | 0.85 | SIGMAR1 (0.45) | SIGMAR1ATMEGFRCFTRGOPC | |
| SCHEMBL27281924 | 0.85 | SIGMAR1 (0.45) | SIGMAR1SMN1; SMN2ATMEGFRCFTR | |
| SCHEMBL28461980 | 0.84 | SIGMAR1 (0.50) | SIGMAR1ATMEGFRCFTRGOPC | |
| SCHEMBL142562 | 0.81 | HSP90AA1 (0.41) | SIGMAR1ATMEGFRCFTRGOPC | |
| SCHEMBL28460053 | 0.80 | SIGMAR1 (0.41) | SIGMAR1MAPTSMN1; SMN2ATMEGFR | |
| SCHEMBL28881800 | 0.80 | SIGMAR1 (0.39) | SIGMAR1GAAATMEGFRHSD17B10 | |
| SCHEMBL28430170 | 0.79 | MMP2 (0.41) | SIGMAR1ATMEGFRCYP2C9 | |
| SCHEMBL27281276 | 0.78 | MMP2 (0.43) | SIGMAR1ATMCYP2C9 | |
| SCHEMBL753626 | 0.76 | SIGMAR1 (0.45) | SIGMAR1MAPTATMCFTRGOPC |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1063967-B1 | COMPOSITIONS FOR REGULATING SKIN APPEARANCE | PROCTER & GAMBLE (US) | 2004-02-11 | — | — | EP | disclosed |