SCHEMBL753626

SCHEMBL753626

O=C1CC(O)(c2ccccc2)Oc2ccccc21

nearest known ligand 0.45

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
SIGMAR1 Q99720 1/20 0.45
ATM Q13315 1/20 0.43
CFTR P13569 1/20 0.42
GOPC Q9HD26 1/20 0.42
RIPK1 Q13546 1/20 0.40
EPHX2 P34913 2/20 0.39
CYP2C9 P11712 1/20 0.39
KDM4E B2RXH2 1/20 0.39
ADORA3 P0DMS8 1/20 0.39
AR P10275 1/20 0.39
CYP19A1 P11511 1/20 0.39
MAOB P27338 1/20 0.39
HSD17B10 Q99714 1/20 0.39
HSD11B1 P28845 1/20 0.38
RAD52 P43351 1/20 0.37
ALOX15 P16050 1/20 0.37
MAPT P10636 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2022537 1.00 SIGMAR1 (0.45) SIGMAR1ATMCFTRGOPCRIPK1
SCHEMBL31074904 0.90 SIGMAR1 (0.38) SIGMAR1ATMCFTRGOPCRIPK1
Pentachlorophenol SCHEMBL4951417 0.89 SIGMAR1 (0.41) SIGMAR1ATMCFTRGOPCRIPK1
SCHEMBL30062559 0.85 MAPT (0.43) SIGMAR1ATMRIPK1KDM4EADORA3
SCHEMBL30872986 0.84 RIPK1 (0.53) ATMRIPK1KDM4ECYP19A1MAOB
SCHEMBL31719029 0.84 SIGMAR1 (0.40) SIGMAR1ATMCFTRGOPCEPHX2
SCHEMBL23610338 0.83 KDM4E (0.58) RIPK1KDM4EARCYP19A1MAOB
SCHEMBL11189211 0.83 MAPT (0.58) ATMRIPK1KDM4EARCYP19A1
SCHEMBL6704259 0.83 SIGMAR1 (0.47) SIGMAR1ATMCFTRGOPCEPHX2
SCHEMBL3289413 0.80 ATM (0.44) SIGMAR1ATMEPHX2CYP2C9KDM4E

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 884 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-12571757-B2 Electrochemical pH sensor ANB SENSORS LTD (GB) 2026-03-10 US claimed
EP-4644551-A1 2-HYDROXYFLAVANONE C-GLYCOSIDE DEHYDRATASE GENE AND USE THEREOF Suntory Holdings Limited (JP) 2025-11-05 EP claimed
EP-4640834-A1 FLAVANONE 2-HYDROXYLASE GENE AND USE OF SAME Suntory Holdings Limited (JP) 2025-10-29 EP claimed
EP-4217721-B1 ELECTROCHEMICAL PH SENSOR ANB SENSORS LTD (GB) 2025-08-27 EP claimed
CN-119930565-A Hydroxy flavonoid derivative and preparation method and application thereof 重庆文理学院 2025-05-06 CN claimed
WO-2024143169-A1 2-HYDROXYFLAVANONE C-GLYCOSIDE DEHYDRATASE GENE AND USE THEREOF サントリーホールディングス株式会社 2024-07-04 WO claimed
WO-2024135619-A1 FLAVANONE 2-HYDROXYLASE GENE AND USE OF SAME サントリーホールディングス株式会社 2024-06-27 WO claimed
CN-113322288-B Novel flavone hydroxylase, microorganism for synthesizing flavone C-glycoside compounds and application thereof 中国科学院分子植物科学卓越创新中心 2023-12-26 CN claimed
CN-113265433-B Bifunctional glycosyltransferase and application thereof 中国科学院分子植物科学卓越创新中心 2023-12-26 CN claimed
CN-113136373-B Carbonoside glycosyltransferase and application thereof 中国科学院分子植物科学卓越创新中心 2023-12-08 CN claimed
CN-101018554-A Topical compositions containing phosphorylated polyphenols AJINOMOTO OMNICHEM S A (BE) 2007-08-15 CN claimed
CN-1217652-C Cosmetic method for caring skin UNILEVER PLC (NL) 2005-09-07 CN claimed
CN-1630521-A Oral compositions and methods for prevention, reduction and treatment of radiation injury THE QUIGLEY CORP (US) 2005-06-22 CN claimed
CN-1594346-A Flavanone glycoside and its preparation and use NANJING UNIVERSITY OF TECHNOLOGY (CN) 2005-03-16 CN claimed
CN-1474684-A Cosmetic method of treating skin 2004-02-11 CN claimed
WO-2003013554-A2 AROMATASE INHIBITORS FROM BROUSSONETIA PAPYRIFERA THE BOARD OF TRUSTEES OF THE UNIVERSITY OF ILLINOIS (US) 2003-02-20 WO claimed
CN-1253493-A Skin care compositions containing combinations of compounds for mimicking effect on skin of retinoic acid UNILEVER PLC (NL) 2000-05-17 CN claimed
CN-1230112-A Method of regulating nicotine metabolism NICOGEN INC (CA) 1999-09-29 CN claimed
EP-0173186-B1 FLAVANON DERIVATIVES MERCK PATENT GmbH (DE) 1988-12-21 EP claimed
EP-0173186-A1 Flavanon derivatives MERCK PATENT GmbH (DE) 1986-03-05 EP claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-12571757-B2 Electrochemical pH sensor SCO2, ASIC1, NOX4 SIGMAR1 2409/4885ATM 1272/4885CFTR 1420/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.