Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA2 | P00918 | 6/20 | 0.48 |
| ▸ | CA1 | P00915 | 3/20 | 0.48 |
| ▸ | NQO2 | P16083 | 1/20 | 0.48 |
| ▸ | MAPT | P10636 | 3/20 | 0.46 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.46 |
| ▸ | LMNA | P02545 | 2/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.46 |
| ▸ | HPGD | P15428 | 1/20 | 0.46 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.46 |
| ▸ | BLM | P54132 | 1/20 | 0.46 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.46 |
| ▸ | NAMPT | P43490 | 1/20 | 0.45 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
| ▸ | CTSK | P43235 | 1/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.41 |
| ▸ | IDO1 | P14902 | 1/20 | 0.41 |
| ▸ | PTGER4 | P35408 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27438451 | 0.88 | CA2 (0.49) | CA2CA1NQO2MAPTHSD17B10 | |
| SCHEMBL233765 | 0.85 | MAPT (0.63) | CA2CA1NQO2MAPTHSD17B10 | |
| SCHEMBL30423117 | 0.85 | MAPT (0.63) | CA2CA1NQO2MAPTHSD17B10 | |
| SCHEMBL21034630 | 0.81 | NQO2 (0.45) | CA2CA1NQO2MAPTHSD17B10 | |
| SCHEMBL8383176 | 0.81 | CYP1A2 (0.51) | CA2CA1MAPTLMNATRPV1 | |
| SCHEMBL25495761 | 0.81 | CA2 (0.46) | CA2CA1NQO2MAPTLMNA | |
| SCHEMBL3698093 | 0.80 | ESRRG (0.53) | CA2CA1NQO2MAPTHSD17B10 | |
| SCHEMBL25495856 | 0.80 | CA2 (0.48) | CA2CA1NQO2MAPTHSD17B10 | |
| SCHEMBL25495764 | 0.80 | CA2 (0.46) | CA2CA1NQO2MAPTHSD17B10 | |
| SCHEMBL8003356 | 0.80 | CA2 (0.48) | CA2CA1NQO2MAPTHSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0904079-B1 | ANTIDIABETIC AGENTS | MERCK & CO INC (US) | 2004-03-24 | — | — | EP | disclosed |
| US-5859051-A | ACETYLPHENOL DERIVATIVES | MERCK & CO., INC. (US) | 1999-01-12 | — | — | US | disclosed |