Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 4/20 | 0.63 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.63 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.63 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.63 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.63 |
| ▸ | LMNA | P02545 | 2/20 | 0.63 |
| ▸ | HPGD | P15428 | 2/20 | 0.63 |
| ▸ | BLM | P54132 | 2/20 | 0.63 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.63 |
| ▸ | CA1 | P00915 | 1/20 | 0.53 |
| ▸ | CA2 | P00918 | 1/20 | 0.53 |
| ▸ | TP53 | P04637 | 1/20 | 0.53 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.53 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.53 |
| ▸ | TSHR | P16473 | 1/20 | 0.53 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.53 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.53 |
| ▸ | THPO | P40225 | 1/20 | 0.53 |
| ▸ | TRPV1 | Q8NER1 | 2/20 | 0.52 |
| ▸ | MEN1 | O00255 | 2/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30423117 | 1.00 | MAPT (0.63) | MAPTHSD17B10HIF1AKDM4EALDH1A1 | |
| SCHEMBL7517472 | 0.91 | MEN1 (0.58) | MAPTHSD17B10HIF1AKDM4EALDH1A1 | |
| SCHEMBL3698093 | 0.89 | ESRRG (0.53) | MAPTHSD17B10HIF1AKDM4EALDH1A1 | |
| SCHEMBL21307485 | 0.87 | CA2 (0.53) | MAPTHSD17B10HIF1AKDM4EALDH1A1 | |
| SCHEMBL9108030 | 0.87 | CA2 (0.53) | MAPTHSD17B10HIF1AKDM4EALDH1A1 | |
| SCHEMBL4451726 | 0.87 | MAPT (0.51) | MAPTHSD17B10HIF1AKDM4EALDH1A1 | |
| SCHEMBL3114793 | 0.87 | CA2 (0.55) | MAPTHSD17B10HIF1AKDM4EALDH1A1 | |
| SCHEMBL8383176 | 0.86 | CYP1A2 (0.51) | MAPTLMNACA1CA2CYP1A2 | |
| SCHEMBL29998779 | 0.86 | MTNR1A (0.59) | LMNACA1CA2TSHRMAPK1 | |
| SCHEMBL69181 | 0.86 | MTNR1A (0.59) | LMNACA1CA2TSHRMAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 84 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113896865-A | Naphthalimide polymer semiconductor containing dopamine-derived side chain and preparation method thereof | 福州大学 | 2022-01-07 | — | — | CN | claimed |
| US-12636371-B2 | Chemically coupled transporter for low-hydrophobicity bioactive drugs into the central nervous system | SKYBIO LLC (US) | 2026-05-26 | — | — | US | disclosed |
| US-20240307371-A1 | BENZOQUINOLINE INHIBITORS OF VESICULAR MONOAMINE TRANSPORTER 2 | AUSPEX PHARMACEUTICALS LLC | 2024-09-19 | — | — | US | disclosed |
| EP-4271415-B1 | CHEMICALLY COUPLED TRANSPORTER FOR DOPAMINE INTO THE CENTRAL NERVOUS SYSTEM | SKYBIO LLC (US) | 2024-07-03 | — | — | EP | disclosed |
| EP-4271415-B1 | CHEMICALLY COUPLED TRANSPORTER FOR DOPAMINE INTO THE CENTRAL NERVOUS SYSTEM | SKYBIO LLC (US) | 2024-07-03 | — | — | EP | disclosed |
| US-20240208992-A1 | MACROCYCLES AS CFTR MODULATORS | IDORSIA PHARMACEUTICALS LTD (CH) | 2024-06-27 | — | — | US | disclosed |
| US-20240197892-A1 | Chemically Coupled Transporter for Low-Hydrophobicity Bioactive Drugs into the Central Nervous System | UNIVERSIDAD DE BUENOS AIRES (AR) | 2024-06-20 | — | — | US | disclosed |
| US-11951170-B2 | Chemically coupled transporter for low-hydrophobicity bioactive drugs into the central nervous system | SKYBIO LLC (US) | 2024-04-09 | — | — | US | disclosed |
| EP-4308575-A1 | MACROCYCLES AS CFTR MODULATORS | Idorsia Pharmaceuticals Ltd (CH) | 2024-01-24 | — | — | EP | disclosed |
| US-20230218768-A1 | Chemically Coupled Transporter for Low-Hydrophobicity Bioactive Drugs into the Central Nervous System | CONSEJO NACIONAL DE INVESTIGACIONES CIENTÍFICAS Y TÉCNICAS (CONICET) (AR) | 2023-07-13 | — | — | US | disclosed |
| EP-1246829-A1 | NOVEL HETEROCYCLES | ARIAD PHARMACEUTICALS, INC. (US) | 2002-10-09 | — | — | EP | disclosed |
| EP-1244679-A1 | PURINE DERIVATIVES | ARIAD PHARMACEUTICALS, INC. (US) | 2002-10-02 | — | — | EP | disclosed |
| US-20020132819-A1 | Novel purinse | ARIAD PHARMACETICALS, INC. | 2002-09-19 | — | — | US | disclosed |
| US-20020103161-A1 | Novel heterocycles | ARIAD PHARMACEUTICALS, INC. | 2002-08-01 | — | — | US | disclosed |
| WO-2001044260-A9 | NOVEL PURINES | ARIAD PHARMA INC (US) | 2002-07-04 | — | — | WO | disclosed |
| US-20020068721-A1 | Purine derivatives | ARIAD PHARMACEUTICALS, INC. | 2002-06-06 | — | — | US | disclosed |
| WO-2001044260-A2 | NOVEL PURINES | ARIAD PHARMACEUTICALS, INC. (US) | 2001-06-21 | — | — | WO | disclosed |
| WO-2001044259-A1 | PURINE DERIVATIVES | ARIAD PHARMACEUTICALS, INC. (US) | 2001-06-21 | — | — | WO | disclosed |
| WO-2001044258-A1 | NOVEL HETEROCYCLES | ARIAD PHARMACEUTICALS, INC. (US) | 2001-06-21 | — | — | WO | disclosed |
| US-4311706-A | ADRENERGIC STIMULANTS | INTERX RESEARCH CORPORATION (US) | 1982-01-19 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (9 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20240307371-A1 | BENZOQUINOLINE INHIBITORS OF VESICULAR MONOAMINE TRANSPORTER 2 | SLC18A2, SLC6A2, SLC18A1 | MAPT 378/4885HSD17B10 695/4885HIF1A 2606/4885 |
| US-20230218768-A1 | Chemically Coupled Transporter for Low-Hydrophobicity Bioactive Drugs into the Central Nervous System | SLC6A3, SLC18A2, TSPO | MAPT 104/4885HSD17B10 2596/4885HIF1A 3351/4885 |
| US-20240197892-A1 | Chemically Coupled Transporter for Low-Hydrophobicity Bioactive Drugs into the Central Nervous System | SLC6A3, SLC18A2, TSPO | MAPT 104/4885HSD17B10 2596/4885HIF1A 3351/4885 |
| US-20020068721-A1 | Purine derivatives | HPRT1, PNP, TYMP | MAPT 4144/4885HSD17B10 2865/4885HIF1A 2381/4885 |
| US-20020132819-A1 | Novel purinse | PURB, NUDT15, NT5C2 | MAPT 4769/4885HSD17B10 4810/4885HIF1A 2673/4885 |
| US-20240208992-A1 | MACROCYCLES AS CFTR MODULATORS | CFTR, PKD1, ARRB1 | MAPT 4728/4885HSD17B10 2713/4885HIF1A 3258/4885 |
| US-11951170-B2 | Chemically coupled transporter for low-hydrophobicity bioactive drugs into the central nervous system | SLC7A1, SLC47A2, ABCB1 | MAPT 65/4885HSD17B10 1336/4885HIF1A 2156/4885 |
| US-20020103161-A1 | Novel heterocycles | BMP2, SOST, BMP4 | MAPT 4739/4885HSD17B10 1549/4885HIF1A 232/4885 |
| US-12636371-B2 | Chemically coupled transporter for low-hydrophobicity bioactive drugs into the central nervous system | SLC6A2, SLC6A3, SLC18A2 | MAPT 101/4885HSD17B10 384/4885HIF1A 2191/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.