Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA2 | P00918 | 6/20 | 0.48 |
| ▸ | CA1 | P00915 | 5/20 | 0.48 |
| ▸ | CA12 | O43570 | 2/20 | 0.47 |
| ▸ | CA9 | Q16790 | 2/20 | 0.47 |
| ▸ | CA7 | P43166 | 1/20 | 0.47 |
| ▸ | PDK2 | Q15119 | 1/20 | 0.47 |
| ▸ | PDK4 | Q16654 | 1/20 | 0.47 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.47 |
| ▸ | MAPT | P10636 | 3/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.46 |
| ▸ | HPGD | P15428 | 2/20 | 0.46 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.46 |
| ▸ | LMNA | P02545 | 2/20 | 0.46 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.46 |
| ▸ | BLM | P54132 | 1/20 | 0.46 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.46 |
| ▸ | NQO2 | P16083 | 1/20 | 0.46 |
| ▸ | NAMPT | P43490 | 1/20 | 0.45 |
| ▸ | GAA | P10253 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5200513 | 0.93 | CA1 (0.47) | CA2CA1CA12CA9CA7 | |
| SCHEMBL30423117 | 0.85 | MAPT (0.63) | CA2CA1MAPTKDM4EALDH1A1 | |
| SCHEMBL233765 | 0.85 | MAPT (0.63) | CA2CA1MAPTKDM4EALDH1A1 | |
| SCHEMBL19026301 | 0.84 | CA1 (0.45) | CA2CA1MAPTKDM4ELMNA | |
| SCHEMBL8383176 | 0.83 | CYP1A2 (0.51) | CA2CA1CA12CA9MAPT | |
| SCHEMBL29998779 | 0.81 | MTNR1A (0.59) | CA2CA1CA12CA9LMNA | |
| SCHEMBL69181 | 0.81 | MTNR1A (0.59) | CA2CA1CA12CA9LMNA | |
| SCHEMBL27438451 | 0.81 | CA2 (0.49) | CA2CA1CA12CA9MAPT | |
| SCHEMBL3698093 | 0.80 | ESRRG (0.53) | CA2CA1CA12CA9MAPT | |
| SCHEMBL3706599 | 0.80 | CA12 (0.58) | CA2CA1CA12CA9CA7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2000027790-A1 | MUTILIN COMPOUNDS | SMITHKLINE BEECHAM P.L.C. (GB) | 2000-05-18 | — | — | WO | disclosed |