Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.71 |
| ▸ | GAA | P10253 | 3/20 | 0.71 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.71 |
| ▸ | MEN1 | O00255 | 1/20 | 0.71 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.58 |
| ▸ | KEAP1 | Q14145 | 3/20 | 0.54 |
| ▸ | LMNA | P02545 | 4/20 | 0.54 |
| ▸ | HTT | P42858 | 3/20 | 0.54 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.54 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.54 |
| ▸ | TUBB4A | P04350 | 1/20 | 0.53 |
| ▸ | TUBB | P07437 | 1/20 | 0.53 |
| ▸ | TUBA3C | P0DPH7 | 1/20 | 0.53 |
| ▸ | TUBA1B | P68363 | 1/20 | 0.53 |
| ▸ | TUBA4A | P68366 | 1/20 | 0.53 |
| ▸ | TUBB4B | P68371 | 1/20 | 0.53 |
| ▸ | TUBB3 | Q13509 | 1/20 | 0.53 |
| ▸ | TUBB2A | Q13885 | 1/20 | 0.53 |
| ▸ | TUBB8 | Q3ZCM7 | 1/20 | 0.53 |
| ▸ | TUBA3E | Q6PEY2 | 1/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6561784 | 0.99 | ALDH1A1 (0.72) | ALDH1A1GAAKMT2AMEN1SMN1; SMN2 | |
| SCHEMBL6562107 | 0.96 | ALDH1A1 (0.69) | ALDH1A1GAAKMT2AMEN1SMN1; SMN2 | |
| SCHEMBL6560637 | 0.94 | KMT2A (0.65) | ALDH1A1GAAKMT2AMEN1SMN1; SMN2 | |
| SCHEMBL7957195 | 0.89 | ALDH1A1 (0.58) | ALDH1A1GAAKMT2AMEN1SMN1; SMN2 | |
| SCHEMBL7943813 | 0.87 | ALDH1A1 (0.57) | ALDH1A1GAAKMT2AMEN1SMN1; SMN2 | |
| SCHEMBL7954177 | 0.84 | GAA (0.53) | ALDH1A1GAAKMT2AMEN1SMN1; SMN2 | |
| SCHEMBL7952653 | 0.82 | GAA (0.51) | ALDH1A1GAAKMT2AMEN1SMN1; SMN2 | |
| SCHEMBL7950725 | 0.82 | GAA (0.51) | ALDH1A1GAAKMT2AMEN1SMN1; SMN2 | |
| SCHEMBL8626209 | 0.80 | LMNA (0.72) | ALDH1A1GAAKMT2ASMN1; SMN2KEAP1 | |
| SCHEMBL12768028 | 0.79 | KEAP1 (0.81) | ALDH1A1GAAKMT2ASMN1; SMN2KEAP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0990645-B1 | NOVEL SULFONAMIDE DERIVATIVES | NIPPON KAYAKU KK (JP) | 2004-07-28 | — | — | EP | disclosed |
| US-6180796-B1 | TUBULIN POLYMERIZATION INHIBITORS | NIPPON KAYAKU KABUSHIKI KAISHA (JP) | 2001-01-30 | — | — | US | disclosed |
| EP-0990645-A1 | NOVEL SULFONAMIDE DERIVATIVES | Nippon Kayaku Kabushiki Kaisha (JP) | 2000-04-05 | — | — | EP | disclosed |