Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | METAP2 | P50579 | 17/20 | 0.55 |
| ▸ | METAP1 | P53582 | 7/20 | 0.55 |
| ▸ | REN | P00797 | 2/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6564722 | 0.81 | METAP2 (0.64) | METAP2METAP1REN | |
| SCHEMBL6565088 | 0.80 | METAP2 (0.56) | METAP2METAP1REN | |
| SCHEMBL6477548 | 0.79 | METAP2 (0.61) | METAP2METAP1REN | |
| SCHEMBL7341595 | 0.79 | METAP2 (0.60) | METAP2METAP1REN | |
| SCHEMBL6475764 | 0.79 | METAP2 (0.60) | METAP2METAP1REN | |
| SCHEMBL9514503 | 0.77 | METAP2 (0.62) | METAP2METAP1REN | |
| SCHEMBL9514498 | 0.77 | METAP2 (0.62) | METAP2METAP1REN | |
| SCHEMBL9514512 | 0.77 | METAP2 (0.62) | METAP2METAP1REN | |
| SCHEMBL7354261 | 0.77 | METAP2 (0.53) | METAP2METAP1REN | |
| SCHEMBL5848395 | 0.76 | METAP2 (0.56) | METAP2METAP1REN |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1272456-B1 | HYDRAZIDE AND ALKOXYAMIDE ANGIOGENESIS INHIBITORS | ABBOTT LAB (US) | 2004-10-27 | — | — | EP | claimed |