Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6476862 | 0.78 | METAP2 (1.00) | METAP2METAP1 | |
| SCHEMBL6476261 | 0.77 | METAP2 (0.64) | METAP2METAP1 | |
| SCHEMBL6477521 | 0.75 | METAP2 (1.00) | METAP2METAP1 | |
| SCHEMBL6487450 | 0.73 | METAP2 (1.00) | METAP2METAP1 | |
| SCHEMBL6563062 | 0.73 | METAP2 (0.66) | METAP2METAP1 | |
| SCHEMBL6477700 | 0.71 | METAP2 (1.00) | METAP2METAP1 | |
| SCHEMBL6563362 | 0.70 | METAP2 (0.62) | METAP2METAP1 | |
| SCHEMBL1157636 | 0.66 | ARG1 (0.60) | METAP2METAP1 | |
| SCHEMBL1157633 | 0.66 | ARG1 (0.60) | METAP2METAP1 | |
| SCHEMBL8084363 | 0.66 | ARG1 (0.60) | METAP2METAP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1272456-B1 | HYDRAZIDE AND ALKOXYAMIDE ANGIOGENESIS INHIBITORS | ABBOTT LAB (US) | 2004-10-27 | — | — | EP | claimed |