Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA1 | P00915 | 12/20 | 0.52 |
| ▸ | CA2 | P00918 | 12/20 | 0.52 |
| ▸ | CA12 | O43570 | 8/20 | 0.52 |
| ▸ | CA9 | Q16790 | 8/20 | 0.52 |
| ▸ | MAPT | P10636 | 3/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.48 |
| ▸ | MEN1 | O00255 | 2/20 | 0.48 |
| ▸ | POLB | P06746 | 2/20 | 0.48 |
| ▸ | PSMD14 | O00487 | 1/20 | 0.48 |
| ▸ | RECQL | P46063 | 1/20 | 0.48 |
| ▸ | CACNA1B | Q00975 | 1/20 | 0.48 |
| ▸ | APBA1 | Q02410 | 1/20 | 0.48 |
| ▸ | CTDSP1 | Q9GZU7 | 1/20 | 0.48 |
| ▸ | SAE1 | Q9UBE0 | 1/20 | 0.48 |
| ▸ | UBA2 | Q9UBT2 | 1/20 | 0.48 |
| ▸ | PTPN7 | P35236 | 1/20 | 0.47 |
| ▸ | CDK2 | P24941 | 1/20 | 0.45 |
| ▸ | CA5A | P35218 | 1/20 | 0.45 |
| ▸ | CA5B | Q9Y2D0 | 1/20 | 0.45 |
| ▸ | CA4 | P22748 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4593089 | 0.87 | POLB (0.56) | KMT2APOLBCDK2 | |
| SCHEMBL19100236 | 0.74 | KDM4E (0.53) | KMT2AMEN1 | |
| SCHEMBL4752431 | 0.72 | MEN1 (0.52) | MAPTKMT2AMEN1CDK2 | |
| SCHEMBL935075 | 0.71 | NPC1 (0.70) | CA1CA2CA12CA9MAPT | |
| SCHEMBL8422583 | 0.69 | CA2 (1.00) | CA1CA2CA12CA9MAPT | |
| SCHEMBL14161532 | 0.69 | MEN1 (0.71) | CA1CA2CA12CA9MAPT | |
| SCHEMBL671546 | 0.69 | CA2 (1.00) | CA1CA2CA12CA9MAPT | |
| SCHEMBL8690975 | 0.68 | KMT2A (0.57) | CA1CA2CA12CA9MAPT | |
| Benzenesulfonamide SCHEMBL29068842 | 0.68 | CA2 (0.48) | CA1CA2CA12CA9CA5A | |
| Benzenesulfonamide SCHEMBL9491339 | 0.67 | CA2 (0.84) | CA1CA2CA12CA9MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0990645-B1 | NOVEL SULFONAMIDE DERIVATIVES | NIPPON KAYAKU KK (JP) | 2004-07-28 | — | — | EP | disclosed |