SCHEMBL8422583

SCHEMBL8422583

NS(=O)(=O)c1ccc(NC(=O)c2ccccc2)cc1

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CA2 P00918 9/20 1.00
CA1 P00915 8/20 1.00
CA9 Q16790 6/20 1.00
CA12 O43570 4/20 1.00
KMT2A Q03164 6/20 0.82
MEN1 O00255 5/20 0.82
PSMD14 O00487 2/20 0.82
POLB P06746 2/20 0.82
MAPT P10636 2/20 0.82
CACNA1B Q00975 2/20 0.82
APBA1 Q02410 2/20 0.82
RECQL P46063 1/20 0.82
CTDSP1 Q9GZU7 1/20 0.82
SAE1 Q9UBE0 1/20 0.82
UBA2 Q9UBT2 1/20 0.82
PRMT1 Q99873 2/20 0.75
PLK1 P53350 1/20 0.73
GAA P10253 1/20 0.71
HPGD P15428 1/20 0.71
NPSR1 Q6W5P4 2/20 0.70

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL18606712 0.85 CA1 (1.00) CA2CA1CA9CA12KMT2A
SCHEMBL14679075 0.84 PRMT1 (0.77) CA2CA1CA9CA12KMT2A
SCHEMBL8421687 0.83 CA2 (0.84) CA2CA1CA9CA12KMT2A
SCHEMBL6225517 0.83 CA1 (0.84) CA2CA1CA9CA12KMT2A
SCHEMBL95883 0.83 CA2 (0.84) CA2CA1CA9CA12KMT2A
SCHEMBL13980021 0.83 CA1 (0.84) CA2CA1CA9CA12KMT2A
SCHEMBL27468719 0.83 CA2 (0.84) CA2CA1CA9CA12KMT2A
SCHEMBL126415 0.83 PTPN1 (0.87) KMT2AMEN1POLBMAPTCACNA1B
SCHEMBL3107195 0.83 PRMT1 (0.75) CA2CA1CA9CA12KMT2A
SCHEMBL10327396 0.83 PRMT1 (0.75) CA2CA1CA9CA12KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 36 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-116660426-B Method for rapidly determining various pesticide veterinary drug residues in animal-derived food and application 山东杰诺检测服务有限公司 2023-10-20 CN claimed
CN-113030308-B Detection method of sulfonamide antibiotics in biogas slurry and sample treatment method thereof 浙江省农业科学院 2022-10-28 CN claimed
CN-110702805-B UPLC-MSMS detection method for establishing 19 sulfanilamide residues in cultured fish based on ASE method of C18 舟山市食品药品检验检测研究院 2021-07-02 CN claimed
CN-108931599-B Method for extracting and analyzing sulfonamides by using DPX gun head type dispersed solid phase microextraction column 无锡微色谱生物科技有限公司 2021-06-01 CN claimed
CN-112858683-A Method for simultaneously and rapidly detecting multiple antibiotics by using immunobiosensor 清华大学 2021-05-28 CN claimed
CN-112595783-A Method for detecting multiple antibiotics in livestock and poultry excrement based on magnetic nanocomposite 山东省农业科学院农业质量标准与检测技术研究所 2021-04-02 CN claimed
CN-110702805-A UPLC-MSMS detection method for establishing 19 sulfanilamide residues in cultured fish based on ASE method of C18 舟山市食品药品检验检测研究院 2020-01-17 CN claimed
EP-0573573-B1 MESOGENIC GLYCIDYL AMINES DOW CHEMICAL CO (US) 1999-09-29 EP claimed
US-12269814-B2 Process for preparing a compound useful to treat mycoses PULMOCIDE LIMITED (GB) 2025-04-08 US disclosed
CN-116773689-A Method for rapidly screening various antibacterial drug residues in livestock manure and application thereof 中国动物卫生与流行病学中心 2023-09-19 CN disclosed
US-11661415-B2 Process for preparing a compound useful to treat mycoses PULMOCIDE LIMITED (GB) 2023-05-30 US disclosed
CN-116165316-A Establishment method of 323 veterinary drug high-throughput screening mass spectrum database 吉林大学 2023-05-26 CN disclosed
CN-113030308-B Detection method of sulfonamide antibiotics in biogas slurry and sample treatment method thereof 浙江省农业科学院 2022-10-28 CN disclosed
CN-114814013-A Method for rapidly screening unknown chemical hazard residues in aquatic products based on high-resolution mass spectrum database 中国海洋大学 2022-07-29 CN disclosed
CN-1377282-A Fatty acid-anticancer conjugates and uses thereof PROTARGA INC (US) 2002-10-30 CN disclosed
EP-0828488-A1 ISOTHIAZOLONES WARNER-LAMBERT COMPANY (US) 1998-03-18 EP disclosed
EP-0775110-A1 ARYLTHIO COMPOUNDS AS ANTIBACTERIAL AND ANTIVIRAL AGENTS WARNER-LAMBERT COMPANY (US) 1997-05-28 EP disclosed
WO-1996038144-A1 ISOTHIAZOLONES WARNER-LAMBERT COMPANY (US) 1996-12-05 WO disclosed
WO-1996004242-A1 ARYLTHIO COMPOUNDS AS ANTIBACTERIAL AND ANTIVIRAL AGENTS WARNER-LAMBERT COMPANY (US) 1996-02-15 WO disclosed
US-5463122-A Amido-phenylthiols or dithiobisbenzamides as bactericides, viricides, retrovirus antigrowth agents; AIDS WARNER-LAMBERT COMPANY (US) 1995-10-31 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-11661415-B2 Process for preparing a compound useful to treat mycoses DPM1, CYP51A1, ERG28 CA2 3243/4885CA1 2628/4885CA9 239/4885
US-12269814-B2 Process for preparing a compound useful to treat mycoses C1R, CBR1, CBR3 CA2 633/4885CA1 2105/4885CA9 294/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.