Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GCK | P35557 | 17/20 | 0.48 |
| ▸ | FFAR2 | O15552 | 1/20 | 0.44 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6563774 | 0.90 | FFAR2 (0.56) | GCKFFAR2KCNH2 | |
| SCHEMBL6595816 | 0.89 | GCK (0.53) | GCKFFAR2KCNH2POLB | |
| SCHEMBL6593978 | 0.87 | GCK (0.48) | GCKFFAR2KCNH2POLB | |
| SCHEMBL6562009 | 0.87 | GCK (0.48) | GCKFFAR2 | |
| SCHEMBL6563810 | 0.86 | KCNH2 (0.45) | GCKFFAR2KCNH2 | |
| SCHEMBL2646316 | 0.85 | GCK (0.51) | GCKFFAR2KCNH2POLB | |
| SCHEMBL2646109 | 0.84 | GCK (0.52) | GCKFFAR2 | |
| SCHEMBL6607782 | 0.83 | GCK (0.45) | GCKFFAR2KCNH2POLB | |
| SCHEMBL6563666 | 0.83 | FFAR2 (0.43) | GCKFFAR2KCNH2 | |
| SCHEMBL6560881 | 0.83 | FFAR2 (0.52) | GCKFFAR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1169312-B1 | GLUCOKINASE ACTIVATORS | HOFFMANN LA ROCHE (CH) | 2004-10-06 | — | — | EP | claimed |