Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FFAR2 | O15552 | 1/20 | 0.43 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.42 |
| ▸ | GCK | P35557 | 13/20 | 0.42 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.41 |
| ▸ | ROCK1 | Q13464 | 1/20 | 0.41 |
| ▸ | KCNQ2 | O43526 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6563294 | 0.93 | L3MBTL1 (0.41) | FFAR2KCNH2GCKROCK2ROCK1 | |
| SCHEMBL6563774 | 0.89 | FFAR2 (0.56) | FFAR2KCNH2GCK | |
| SCHEMBL6563810 | 0.88 | KCNH2 (0.45) | FFAR2KCNH2GCK | |
| SCHEMBL2658530 | 0.86 | L3MBTL1 (0.46) | FFAR2KCNH2GCKROCK2ROCK1 | |
| SCHEMBL2644873 | 0.86 | L3MBTL1 (0.46) | FFAR2KCNH2GCKROCK2ROCK1 | |
| SCHEMBL2645895 | 0.85 | SMN1; SMN2 (0.48) | FFAR2KCNH2GCK | |
| SCHEMBL2657991 | 0.85 | SMN1; SMN2 (0.48) | FFAR2KCNH2GCK | |
| SCHEMBL6595816 | 0.84 | GCK (0.53) | FFAR2KCNH2GCK | |
| SCHEMBL6561839 | 0.83 | GCK (0.48) | FFAR2KCNH2GCK | |
| SCHEMBL27548008 | 0.83 | FFAR2 (0.46) | FFAR2KCNH2GCKROCK2ROCK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1169312-B1 | GLUCOKINASE ACTIVATORS | HOFFMANN LA ROCHE (CH) | 2004-10-06 | — | — | EP | claimed |