Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PIK3CA | P42336 | 11/20 | 0.44 |
| ▸ | MTOR | P42345 | 11/20 | 0.44 |
| ▸ | ACACB | O00763 | 1/20 | 0.36 |
| ▸ | F7 | P08709 | 2/20 | 0.35 |
| ▸ | F3 | P13726 | 2/20 | 0.35 |
| ▸ | F2 | P00734 | 4/20 | 0.35 |
| ▸ | F10 | P00742 | 4/20 | 0.35 |
| ▸ | PLG | P00747 | 3/20 | 0.35 |
| ▸ | PLAU | P00749 | 3/20 | 0.35 |
| ▸ | PLAT | P00750 | 3/20 | 0.35 |
| ▸ | KLK1 | P06870 | 1/20 | 0.35 |
| ▸ | KLK5 | Q9Y337 | 1/20 | 0.35 |
| ▸ | ITGB3 | P05106 | 1/20 | 0.34 |
| ▸ | ITGA2B | P08514 | 1/20 | 0.34 |
| ▸ | F9 | P00740 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6563617 | 0.87 | PIK3CA (0.37) | PIK3CAMTORF2F10PLG | |
| SCHEMBL6561958 | 0.86 | ACACB (0.49) | ACACBF7F3F2F10 | |
| SCHEMBL6561944 | 0.86 | F10 (0.43) | PIK3CAMTORACACBF10 | |
| SCHEMBL6565215 | 0.84 | PIK3CA (0.38) | PIK3CAMTORACACB | |
| SCHEMBL6565512 | 0.82 | GAA (0.40) | ACACBF2F10PLAU | |
| SCHEMBL7809950 | 0.82 | PIK3CA (0.40) | PIK3CAMTORACACBF2 | |
| SCHEMBL6561848 | 0.80 | KDM1A (0.41) | PIK3CAMTORACACBF2PLG | |
| SCHEMBL6565424 | 0.79 | ITGB3 (0.42) | F2ITGB3ITGA2B | |
| SCHEMBL6564957 | 0.78 | F2 (0.38) | F7F3F2F10PLAU | |
| SCHEMBL6565351 | 0.78 | F10 (0.44) | ACACBF7F3F2F10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1140802-B1 | SUBSTITUTED ARYL AND HETEROARYL DERIVATIVES, THEIR PRODUCTION AND THEIR USE AS MEDICINES | BOEHRINGER INGELHEIM PHARMA (DE) | 2004-03-17 | — | — | EP | disclosed |
| US-6479524-B1 | TO PROLONG THE THROMBIN TIME | BOEHRINGER INGELHEIM PHARMA KG (DE) | 2002-11-12 | — | — | US | disclosed |