Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | F10 | P00742 | 2/20 | 0.43 |
| ▸ | PIK3CA | P42336 | 3/20 | 0.43 |
| ▸ | MTOR | P42345 | 3/20 | 0.43 |
| ▸ | ACACB | O00763 | 3/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | HPGD | P15428 | 2/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | PABPC1 | P11940 | 1/20 | 0.39 |
| ▸ | WDR5 | P61964 | 1/20 | 0.39 |
| ▸ | MYC | P01106 | 1/20 | 0.38 |
| ▸ | RORC | P51449 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | HTT | P42858 | 1/20 | 0.37 |
| ▸ | ATM | Q13315 | 1/20 | 0.37 |
| ▸ | GAA | P10253 | 1/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6561958 | 0.91 | ACACB (0.49) | F10ACACBKMT2AHPGD | |
| SCHEMBL6562282 | 0.86 | PIK3CA (0.44) | F10PIK3CAMTORACACB | |
| SCHEMBL6561848 | 0.84 | KDM1A (0.41) | PIK3CAMTORACACB | |
| SCHEMBL6563060 | 0.84 | SMN1; SMN2 (0.41) | F10PIK3CAMTORACACBHPGD | |
| SCHEMBL6563686 | 0.83 | F10 (0.46) | F10KMT2AHPGDSMN1; SMN2ALDH1A1 | |
| SCHEMBL6561973 | 0.83 | JAK1 (0.38) | PIK3CAMTORACACBKMT2AHPGD | |
| SCHEMBL6565351 | 0.82 | F10 (0.44) | F10ACACB | |
| SCHEMBL5885702 | 0.82 | ACACB (0.46) | F10ACACBKMT2AHPGDALDH1A1 | |
| SCHEMBL6565512 | 0.81 | GAA (0.40) | F10ACACBKMT2AHPGDALDH1A1 | |
| Hydrochloric Acid SCHEMBL5886024 | 0.81 | ACACB (0.46) | F10ACACBKMT2AHPGDALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1140802-B1 | SUBSTITUTED ARYL AND HETEROARYL DERIVATIVES, THEIR PRODUCTION AND THEIR USE AS MEDICINES | BOEHRINGER INGELHEIM PHARMA (DE) | 2004-03-17 | — | — | EP | disclosed |
| US-6479524-B1 | TO PROLONG THE THROMBIN TIME | BOEHRINGER INGELHEIM PHARMA KG (DE) | 2002-11-12 | — | — | US | disclosed |