Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.52 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.52 |
| ▸ | NPC1 | O15118 | 1/20 | 0.47 |
| ▸ | RAB9A | P51151 | 1/20 | 0.47 |
| ▸ | GAA | P10253 | 2/20 | 0.46 |
| ▸ | LMNA | P02545 | 1/20 | 0.46 |
| ▸ | TP53 | P04637 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.43 |
| ▸ | NLRP3 | Q96P20 | 2/20 | 0.42 |
| ▸ | MEN1 | O00255 | 2/20 | 0.42 |
| ▸ | TNF | P01375 | 1/20 | 0.42 |
| ▸ | NOD2 | Q9HC29 | 1/20 | 0.42 |
| ▸ | NOD1 | Q9Y239 | 1/20 | 0.42 |
| ▸ | POLB | P06746 | 1/20 | 0.42 |
| ▸ | HTT | P42858 | 1/20 | 0.42 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6561899 | 0.81 | ALDH1A1 (0.60) | ALDH1A1KDM4ENPC1RAB9AGAA | |
| SCHEMBL6561870 | 0.81 | ALDH1A1 (0.60) | ALDH1A1KDM4ENPC1RAB9AGAA | |
| SCHEMBL6560700 | 0.75 | NPC1 (0.51) | ALDH1A1KDM4ENPC1RAB9ALMNA | |
| SCHEMBL6560672 | 0.74 | CACNA1B (0.52) | ALDH1A1KDM4ENPC1RAB9ATP53 | |
| SCHEMBL6561772 | 0.74 | POLB (0.44) | ALDH1A1KDM4ENPC1RAB9ATP53 | |
| SCHEMBL2298593 | 0.71 | ALDH1A1 (0.56) | ALDH1A1KDM4ENPC1RAB9AGAA | |
| SCHEMBL2456604 | 0.70 | NLRP3 (0.74) | ALDH1A1KDM4ERAB9ALMNATP53 | |
| SCHEMBL2784166 | 0.70 | ALDH1A1 (0.70) | ALDH1A1KDM4ENPC1RAB9AGAA | |
| SCHEMBL8937491 | 0.69 | ALDH1A1 (0.60) | ALDH1A1KDM4ENPC1RAB9AGAA | |
| SCHEMBL8937488 | 0.69 | ALDH1A1 (0.60) | ALDH1A1KDM4ENPC1RAB9AGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0944581-A4 | PROCESS OF PREPARING SUBSTITUTED ACRYLAMIDES | LILLY CO ELI (US) | 2004-09-08 | — | — | EP | disclosed |
| EP-0944581-A1 | PROCESS OF PREPARING SUBSTITUTED ACRYLAMIDES | ELI LILLY AND COMPANY (US) | 1999-09-29 | — | — | EP | disclosed |
| WO-1998022429-A1 | PROCESS OF PREPARING SUBSTITUTED ACRYLAMIDES | ELI LILLY AND COMPANY (US) | 1998-05-28 | — | — | WO | disclosed |