Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOB | P27338 | 2/20 | 0.45 |
| ▸ | MTOR | P42345 | 1/20 | 0.45 |
| ▸ | HPGDS | O60760 | 1/20 | 0.45 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.43 |
| ▸ | KDR | P35968 | 2/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | NPC1 | O15118 | 2/20 | 0.41 |
| ▸ | RAB9A | P51151 | 2/20 | 0.41 |
| ▸ | CES2 | O00748 | 3/20 | 0.41 |
| ▸ | CES1 | P23141 | 2/20 | 0.41 |
| ▸ | NR4A1 | P22736 | 1/20 | 0.40 |
| ▸ | NR4A2 | P43354 | 1/20 | 0.40 |
| ▸ | NR4A3 | Q92570 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 2/20 | 0.40 |
| ▸ | MAPT | P10636 | 2/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.40 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.40 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6561899 | 0.82 | ALDH1A1 (0.60) | KDM4EALDH1A1NPC1RAB9ALMNA | |
| SCHEMBL6561870 | 0.82 | ALDH1A1 (0.60) | KDM4EALDH1A1NPC1RAB9ALMNA | |
| SCHEMBL6563253 | 0.75 | TSHR (0.45) | KDM4ENPC1RAB9ACES2CES1 | |
| SCHEMBL6563249 | 0.75 | TSHR (0.45) | KDM4ENPC1RAB9ACES2CES1 | |
| SCHEMBL6561874 | 0.75 | PLK1 (0.47) | TRPV1ALDH1A1NPC1RAB9ANR4A1 | |
| SCHEMBL6562127 | 0.75 | PLK1 (0.47) | TRPV1ALDH1A1NPC1RAB9ANR4A1 | |
| SCHEMBL3945565 | 0.74 | MAOB (0.43) | MAOBMTORHPGDSALDH1A1CES2 | |
| SCHEMBL3945568 | 0.74 | MAOB (0.43) | MAOBMTORHPGDSALDH1A1CES2 | |
| SCHEMBL3945561 | 0.74 | MAOB (0.43) | MAOBMTORHPGDSALDH1A1CES2 | |
| SCHEMBL6561880 | 0.73 | PLK1 (0.48) | KDM4ENPC1RAB9ACES2CES1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0944581-A4 | PROCESS OF PREPARING SUBSTITUTED ACRYLAMIDES | LILLY CO ELI (US) | 2004-09-08 | — | — | EP | disclosed |
| EP-0944581-A1 | PROCESS OF PREPARING SUBSTITUTED ACRYLAMIDES | ELI LILLY AND COMPANY (US) | 1999-09-29 | — | — | EP | disclosed |
| WO-1998022429-A1 | PROCESS OF PREPARING SUBSTITUTED ACRYLAMIDES | ELI LILLY AND COMPANY (US) | 1998-05-28 | — | — | WO | disclosed |