Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | JAK1 | P23458 | 5/20 | 0.38 |
| ▸ | ACACB | O00763 | 3/20 | 0.38 |
| ▸ | JAK2 | O60674 | 3/20 | 0.38 |
| ▸ | PIK3CA | P42336 | 2/20 | 0.37 |
| ▸ | MTOR | P42345 | 2/20 | 0.37 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | CD274 | Q9NZQ7 | 1/20 | 0.36 |
| ▸ | PTPN11 | Q06124 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | WDR5 | P61964 | 1/20 | 0.35 |
| ▸ | HPGD | P15428 | 1/20 | 0.35 |
| ▸ | PABPC1 | P11940 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6565533 | 0.93 | ACACB (0.45) | JAK1ACACBJAK2PTPN11KMT2A | |
| SCHEMBL6565215 | 0.88 | PIK3CA (0.38) | JAK1ACACBPIK3CAMTORCD274 | |
| SCHEMBL6565221 | 0.86 | SMN1; SMN2 (0.41) | SMN1; SMN2CD274KMT2AHPGD | |
| SCHEMBL6563299 | 0.85 | NAMPT (0.40) | ACACB | |
| SCHEMBL6561810 | 0.85 | HSD11B1 (0.40) | ACACBJAK2PTPN11 | |
| SCHEMBL6565339 | 0.84 | HPGD (0.39) | ACACBPIK3CAMTORPTPN11KMT2A | |
| SCHEMBL6565417 | 0.84 | PTPN11 (0.36) | ACACBPTPN11HPGD | |
| SCHEMBL6561944 | 0.83 | F10 (0.43) | ACACBPIK3CAMTORSMN1; SMN2KMT2A | |
| SCHEMBL6563328 | 0.83 | ACACB (0.36) | JAK1ACACBPTPN11KMT2A | |
| SCHEMBL7674981 | 0.82 | ABL1 (0.43) | ACACBSMN1; SMN2PTPN11KMT2AHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1140802-B1 | SUBSTITUTED ARYL AND HETEROARYL DERIVATIVES, THEIR PRODUCTION AND THEIR USE AS MEDICINES | BOEHRINGER INGELHEIM PHARMA (DE) | 2004-03-17 | — | — | EP | disclosed |
| US-6479524-B1 | TO PROLONG THE THROMBIN TIME | BOEHRINGER INGELHEIM PHARMA KG (DE) | 2002-11-12 | — | — | US | disclosed |