SCHEMBL6562035

SCHEMBL6562035

Cc1cccc(C)c1OP(=O)(Oc1ccccc1)Oc1cccc(OP(=O)(Oc2ccccc2)Oc2c(C)cccc2C)c1

nearest known ligand 0.46

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
CYP3A4 P08684 2/20 0.46
TSHR P16473 2/20 0.46
L3MBTL1 Q9Y468 5/20 0.45
NPSR1 Q6W5P4 2/20 0.45
MAPK1 P28482 2/20 0.45
HCRTR1 O43613 2/20 0.43
GAA P10253 1/20 0.43
KMT2A Q03164 3/20 0.42
MEN1 O00255 2/20 0.42
TDP1 Q9NUW8 2/20 0.41
SRC P12931 1/20 0.41
ALDH1A1 P00352 1/20 0.41
HPGD P15428 2/20 0.41
LMNA P02545 3/20 0.40
MAPT P10636 1/20 0.40
HTT P42858 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL14431856 1.00 CYP3A4 (0.46) CYP3A4TSHRL3MBTL1NPSR1MAPK1
SCHEMBL133436 0.95 CYP3A4 (0.45) CYP3A4TSHRL3MBTL1NPSR1MAPK1
SCHEMBL8073336 0.95 CYP3A4 (0.50) CYP3A4TSHRL3MBTL1NPSR1MAPK1
SCHEMBL10633095 0.95 CYP3A4 (0.50) CYP3A4TSHRL3MBTL1NPSR1MAPK1
SCHEMBL13221571 0.89 MAPT (0.39) CYP3A4TSHRL3MBTL1NPSR1MAPK1
SCHEMBL131318 0.87 CYP3A4 (0.59) CYP3A4TSHRL3MBTL1MAPK1GAA
SCHEMBL8153775 0.86 ALDH1A1 (0.50) CYP3A4TSHRL3MBTL1NPSR1MAPK1
SCHEMBL11985784 0.85 L3MBTL1 (0.39) CYP3A4TSHRL3MBTL1NPSR1MAPK1
SCHEMBL78015 0.85 SRC (0.54) CYP3A4TSHRL3MBTL1NPSR1MAPK1
SCHEMBL25513746 0.85 SRC (0.54) CYP3A4TSHRL3MBTL1NPSR1MAPK1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0994155-B1 Flame-retardant polycarbonate resin composition and its injection moldings IDEMITSU PETROCHEMICAL CO (JP) 2004-01-21 EP disclosed
US-6331584-B1 BLEND OF POLYCARBONATE, PHOSPHATE, STYRENIC RESIN AND A POLYGLYCERIN OR POLYALKYLENE ETHER IDEMITSU PETROCHEMICAL CO., LTD. (JP) 2001-12-18 US disclosed
EP-0994155-A2 Flame-retardant polycarbonate resin composition and its injection moldings IDEMITSU PETROCHEMICAL CO., LTD. (JP) 2000-04-19 EP disclosed