SCHEMBL8073336

SCHEMBL8073336

Cc1cccc(C)c1OP(=O)(Oc1ccccc1)Oc1c(C)cccc1C

nearest known ligand 0.50

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
CYP3A4 P08684 2/20 0.50
TSHR P16473 2/20 0.50
SRC P12931 1/20 0.45
L3MBTL1 Q9Y468 5/20 0.44
TDP1 Q9NUW8 2/20 0.44
MEN1 O00255 2/20 0.42
KMT2A Q03164 2/20 0.42
LMNA P02545 2/20 0.42
HCRTR1 O43613 1/20 0.41
MAPK1 P28482 2/20 0.41
NPSR1 Q6W5P4 2/20 0.41
ALDH1A1 P00352 1/20 0.41
HPGD P15428 2/20 0.41
KDM4E B2RXH2 1/20 0.40
GAA P10253 1/20 0.39
SMN1; SMN2 Q16637 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10633095 1.00 CYP3A4 (0.50) CYP3A4TSHRSRCL3MBTL1TDP1
SCHEMBL6562035 0.95 CYP3A4 (0.46) CYP3A4TSHRSRCL3MBTL1TDP1
SCHEMBL14431856 0.95 CYP3A4 (0.46) CYP3A4TSHRSRCL3MBTL1TDP1
SCHEMBL131318 0.92 CYP3A4 (0.59) CYP3A4TSHRSRCL3MBTL1TDP1
SCHEMBL133436 0.89 CYP3A4 (0.45) CYP3A4TSHRSRCL3MBTL1TDP1
SCHEMBL940949 0.88 MAPT (0.45) CYP3A4TSHRL3MBTL1TDP1KMT2A
SCHEMBL328912 0.87 CYP3A4 (0.53) CYP3A4TSHRL3MBTL1TDP1MEN1
SCHEMBL145024 0.87 CYP3A4 (0.70) CYP3A4TSHRL3MBTL1TDP1MEN1
SCHEMBL10781123 0.85 ALDH1A1 (0.52) CYP3A4TSHRSRCL3MBTL1TDP1
SCHEMBL10870605 0.85 ALDH1A1 (0.52) CYP3A4TSHRSRCL3MBTL1TDP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 20 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0007460-B1 FLAME-RETARDANT POLYMER COMPOSITIONS CIBA-GEIGY AG (CH) 1982-09-15 EP claimed
JP-11335927-A None JP disclosed
CN-110036072-B Polycarbonate resin composition 大赛璐塑料株式会社 2023-01-31 CN disclosed
JP-2000008225-A ELASTIC CONJUGATE FILAMENT EXCELLENT IN FLAME RETARDANCE TOYOBO CO LTD 2000-01-11 JP disclosed
JP-H11335927-A ELASTIC MONOFILAMENT HAVING EXCELLENT FLAME RESISTANCE AND DURABILITY TOYOBO CO LTD 1999-12-07 JP disclosed
EP-0173856-B1 FLAME RESISTANT POLYCARBONATE MOULDING COMPOSITIONS BAYER AG (DE) 1988-11-17 EP disclosed
EP-0103231-B1 FLAME-RETARDANT POLYMER MIXTURES BAYER AG (DE) 1988-09-28 EP disclosed
EP-0106082-B1 POLYPHOSPHATES, THEIR PREPARATION AND THEIR USE BAYER AG (DE) 1986-12-17 EP disclosed
EP-0173869-A1 Flame-retardant thermoplastic polymer composition BAYER AG (DE) 1986-03-12 EP disclosed
EP-0173856-A1 Flame resistant polycarbonate moulding compositions BAYER AG (DE) 1986-03-12 EP disclosed
US-4491656-A HINDERED AROMATIC DIOL COPOLYMERS BAYER AKTIENGESELLSCHAFT (DE) 1985-01-01 US disclosed
US-4482693-A 1,1,32,4,6-PENTAMETHYL-3/3,5-DIMETHYL-4-HYDROXY/INDAN-5-0L BAYER AKTIENGESELLSCHAFT (DE) 1984-11-13 US disclosed
US-4481338-A POLYCARBONATE-POLYPHOSPHATE BLEND BAYER AKTIENGESELLSCHAFT (DE) 1984-11-06 US disclosed
US-4463130-A POLYCARBONATE, STYRENE POLYMER AND POLYPHOSPHATE POLYMER; MOLDING MATERIALS BAYER AKTIENGESELLSCHAFT (DE) 1984-07-31 US disclosed
EP-0106082-A1 Polyphosphates, their preparation and their use BAYER AG (DE) 1984-04-25 EP disclosed
EP-0103227-A1 Process for preparing polyphosphates, polyphosphates obtained by that process, and their use BAYER AG (DE) 1984-03-21 EP disclosed
EP-0103230-A2 Flame-retardant polymer mixtures BAYER AG (DE) 1984-03-21 EP disclosed
EP-0103231-A2 Flame-retardant polymer mixtures BAYER AG (DE) 1984-03-21 EP disclosed
EP-0007460-B1 FLAME-RETARDANT POLYMER COMPOSITIONS CIBA-GEIGY AG (CH) 1982-09-15 EP disclosed
EP-0007460-A1 Flame-retardant polymer compositions CIBA-GEIGY AG (CH) 1980-02-06 EP disclosed