SCHEMBL6562054

SCHEMBL6562054

C=CC(=O)OC(C)[N+](C)(C)Cc1ccc(C[N+](C)(C)C(C)C)cc1

nearest known ligand 0.38

Predicted protein targets (top 10)

geneUniProtsupporting neighboursconfidence
THRB P10828 3/20 0.38
TSHR P16473 1/20 0.34
ACACB O00763 1/20 0.32
POLB P06746 1/20 0.30
BCHE P06276 1/20 0.30
ACHE P22303 1/20 0.30
CYP1A2 P05177 1/20 0.30
CYP2D6 P10635 1/20 0.30
MAPK1 P28482 1/20 0.30
HSD17B10 Q99714 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Hydrochloric Acid SCHEMBL7605623 0.99 THRB (0.37) THRBTSHRACACB
Hydrochloric Acid SCHEMBL28406302 0.89 TGM2 (0.36) THRBTSHRACACBCYP1A2
SCHEMBL2743760 0.88 TSHR (0.41) THRBTSHRPOLB
SCHEMBL6563556 0.87 THRB (0.38) THRBTSHRACACB
Hydrochloric Acid SCHEMBL1683544 0.87 ALDH1A1 (0.40) THRBTSHRPOLB
Iodide SCHEMBL29161127 0.87 TSHR (0.40) THRBTSHRPOLB
Bromide SCHEMBL28360563 0.87 TSHR (0.40) THRBTSHRPOLBACHE
Fluoride Ion SCHEMBL29161106 0.87 TSHR (0.40) THRBTSHRPOLB
Hydrochloric Acid SCHEMBL7604275 0.86 THRB (0.38) THRBTSHRACACB
SCHEMBL6560968 0.83 THRB (0.35) THRBTSHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1201645-B1 Acrylates having several quaternary amino groups in the alcohol moiety, process for their preparation and (co)polymers obtained from these monomers ATOFINA (FR) 2004-09-22 EP disclosed
US-6469204-B2 P-XYLYLENE DICHLORIDE IS REACTED WITH DIMETHYLETHYL OR DIMETHYLISOPROPYLAMINE TO PRODUCE AN INTERMEDIATE, REACTING PRODUCT WITH (METH)ACRYLIC ACID, DIMETHYLAMINOETHYL ESTER OR (METH)ACRYLIC ACID, TETRAMETHYLDIAMINOISOPROPYL ESTER ATOFINA (FR) 2002-10-22 US disclosed
EP-1201645-A2 Acrylates having several quaternary amino groups in the alcohol moiety, process for their preparation and (co)polymers obtained from these monomers Atofina (FR) 2002-05-02 EP disclosed