Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 5/20 | 0.57 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.57 |
| ▸ | LMNA | P02545 | 3/20 | 0.57 |
| ▸ | HTT | P42858 | 3/20 | 0.57 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.57 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.57 |
| ▸ | RAB9A | P51151 | 2/20 | 0.53 |
| ▸ | POLB | P06746 | 1/20 | 0.49 |
| ▸ | MEN1 | O00255 | 2/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.49 |
| ▸ | GAA | P10253 | 1/20 | 0.48 |
| ▸ | CA1 | P00915 | 2/20 | 0.47 |
| ▸ | CA2 | P00918 | 2/20 | 0.47 |
| ▸ | CA9 | Q16790 | 2/20 | 0.47 |
| ▸ | CA14 | Q9ULX7 | 2/20 | 0.47 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.45 |
| ▸ | NPC1 | O15118 | 1/20 | 0.44 |
| ▸ | NCOA1 | Q15788 | 1/20 | 0.43 |
| ▸ | NCOA3 | Q9Y6Q9 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5755108 | 0.84 | MAPT (0.54) | MAPTALDH1A1LMNAHTTSMN1; SMN2 | |
| SCHEMBL5756449 | 0.79 | MAPT (0.49) | MAPTALDH1A1LMNAHTTSMN1; SMN2 | |
| SCHEMBL5245531 | 0.76 | ALDH1A1 (0.47) | MAPTALDH1A1LMNAHTTSMN1; SMN2 | |
| SCHEMBL5243650 | 0.74 | ROCK1 (0.45) | MAPTALDH1A1LMNAHTTSMN1; SMN2 | |
| SCHEMBL10620565 | 0.72 | MEN1 (0.68) | MAPTALDH1A1LMNAHTTSMN1; SMN2 | |
| SCHEMBL8647897 | 0.71 | EGFR (0.67) | MAPTALDH1A1LMNAHTTSMN1; SMN2 | |
| SCHEMBL9044161 | 0.71 | ALDH1A1 (0.47) | MAPTALDH1A1LMNAHTTSMN1; SMN2 | |
| SCHEMBL3303857 | 0.71 | MAPT (0.46) | MAPTALDH1A1LMNAHTTSMN1; SMN2 | |
| SCHEMBL20328418 | 0.70 | TDP1 (0.66) | MAPTALDH1A1LMNAHTTSMN1; SMN2 | |
| SCHEMBL20328412 | 0.70 | TDP1 (0.66) | MAPTALDH1A1LMNAHTTSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6828443-B1 | Dyes and colorants | HENKEL KOMMANDITGESELLSCHAFT AUF AKTIEN (DE) | 2004-12-07 | — | — | US | disclosed |
| EP-1189993-B1 | NOVEL DYES AND COLORANTS | HENKEL KGAA (DE) | 2004-02-18 | — | — | EP | disclosed |
| EP-1189993-A1 | NOVEL DYES AND COLORANTS | Henkel Kommanditgesellschaft auf Aktien (DE) | 2002-03-27 | — | — | EP | disclosed |
| WO-2001002492-A1 | NOVEL DYES AND COLORANTS | HENKEL KOMMANDITGESELLSCHAFT AUF AKTIEN (DE) | 2001-01-11 | — | — | WO | disclosed |