Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 7/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.49 |
| ▸ | LMNA | P02545 | 3/20 | 0.49 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.49 |
| ▸ | HTT | P42858 | 2/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.49 |
| ▸ | ROCK1 | Q13464 | 1/20 | 0.47 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.46 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.46 |
| ▸ | MEN1 | O00255 | 4/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.46 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.44 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.44 |
| ▸ | HPGD | P15428 | 1/20 | 0.44 |
| ▸ | CA1 | P00915 | 1/20 | 0.43 |
| ▸ | CA2 | P00918 | 1/20 | 0.43 |
| ▸ | CA9 | Q16790 | 1/20 | 0.43 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.43 |
| ▸ | RAB9A | P51151 | 2/20 | 0.43 |
| ▸ | NPC1 | O15118 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5755108 | 0.82 | MAPT (0.54) | MAPTALDH1A1LMNAMAPK1HTT | |
| Hydrochloric Acid SCHEMBL5758288 | 0.79 | GRIN2D (0.43) | MAPTALDH1A1MAPK1SMN1; SMN2MEN1 | |
| SCHEMBL6562166 | 0.79 | MAPT (0.57) | MAPTALDH1A1LMNAMAPK1HTT | |
| SCHEMBL27604266 | 0.74 | PTK2 (0.51) | ALDH1A1SMN1; SMN2HPGDRAB9ANPC1 | |
| SCHEMBL8649221 | 0.72 | ROCK1 (0.50) | MAPTALDH1A1LMNAMAPK1HTT | |
| SCHEMBL9044161 | 0.72 | ALDH1A1 (0.47) | MAPTALDH1A1LMNAMAPK1HTT | |
| SCHEMBL6948959 | 0.72 | KDM4E (0.39) | ALDH1A1MAPK1SMN1; SMN2MEN1KMT2A | |
| SCHEMBL8931660 | 0.71 | MAPT (0.69) | MAPTALDH1A1LMNAMAPK1SMN1; SMN2 | |
| SCHEMBL18187707 | 0.71 | ROCK1 (0.47) | MAPTALDH1A1LMNAROCK1ALOX12 | |
| SCHEMBL31554509 | 0.70 | ALDH1A1 (0.45) | MAPTALDH1A1LMNAMAPK1HTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1349535-B1 | INDOLE/INDOLINE BASED HYBRID DYES AND INDOLE/INDOLINE BASED HYBRID DYE INTERMEDIATE PRODUCTS | HENKEL KGAA (DE) | 2006-11-02 | — | — | EP | disclosed |
| US-6736862-B2 | DYEING KERATIN FIBERS; HAIR DYES | HENKEL KOMMANDITGESELLSCHAFT AUF AKTIEN (DE) | 2004-05-18 | — | — | US | disclosed |
| US-20040006834-A1 | Indole/indoline based hybrid dyes and indole/indoline based hybrid dye intermediate products | HENKEL AG & CO. KGAA (DE) | 2004-01-15 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040006834-A1 | Indole/indoline based hybrid dyes and indole/indoline based hybrid dye intermediate products | KRT18, TYR, IDO1 | MAPT 1133/4885ALDH1A1 1619/4885LMNA 283/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.