Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LOXL2 | Q9Y4K0 | 2/20 | 0.54 |
| ▸ | CYP2A6 | P11509 | 2/20 | 0.54 |
| ▸ | SAE1 | Q9UBE0 | 1/20 | 0.48 |
| ▸ | UBA2 | Q9UBT2 | 1/20 | 0.48 |
| ▸ | MAPT | P10636 | 1/20 | 0.48 |
| ▸ | MMP12 | P39900 | 1/20 | 0.45 |
| ▸ | MMP13 | P45452 | 1/20 | 0.45 |
| ▸ | CYP19A1 | P11511 | 2/20 | 0.44 |
| ▸ | HTT | P42858 | 1/20 | 0.44 |
| ▸ | KCNJ1 | P48048 | 1/20 | 0.44 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.44 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.43 |
| ▸ | CTBP2 | P56545 | 1/20 | 0.43 |
| ▸ | IDO1 | P14902 | 2/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | CA12 | O43570 | 1/20 | 0.42 |
| ▸ | CA2 | P00918 | 1/20 | 0.42 |
| ▸ | CA3 | P07451 | 1/20 | 0.42 |
| ▸ | CA6 | P23280 | 1/20 | 0.42 |
| ▸ | CA9 | Q16790 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11139354 | 0.82 | CYP3A4 (0.42) | ALDH1A1TSHR | |
| SCHEMBL249189 | 0.80 | LOXL2 (0.58) | LOXL2CYP2A6SAE1UBA2MAPT | |
| SCHEMBL1344068 | 0.79 | LOXL2 (0.65) | LOXL2CYP2A6SAE1UBA2CYP19A1 | |
| SCHEMBL10821186 | 0.76 | LOXL2 (0.54) | LOXL2CYP2A6MAPTCYP19A1HTT | |
| SCHEMBL16150506 | 0.76 | LOXL2 (0.54) | LOXL2CYP2A6SAE1UBA2MAPT | |
| SCHEMBL595992 | 0.75 | LOXL2 (0.58) | LOXL2CYP2A6SAE1UBA2MAPT | |
| SCHEMBL4797601 | 0.74 | GLA (0.51) | MMP12MMP13CYP19A1HRH3ALDH1A1 | |
| SCHEMBL1004267 | 0.74 | LOXL2 (0.64) | LOXL2CYP2A6SAE1UBA2MMP12 | |
| SCHEMBL18427888 | 0.74 | HRH3 (0.41) | MMP12MMP13CYP19A1HTTHRH3 | |
| Hydrogen Sulfide SCHEMBL27473258 | 0.73 | LOXL2 (0.56) | LOXL2CYP2A6SAE1UBA2MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 34 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116891476-A | Fluorescent probe for rapidly detecting hydrogen sulfide gas and preparation method and application thereof | 云南电力试验研究院(集团)有限公司 | 2023-10-17 | — | — | CN | claimed |
| CN-116891476-A | Fluorescent probe for rapidly detecting hydrogen sulfide gas and preparation method and application thereof | 云南电力试验研究院(集团)有限公司 | 2023-10-17 | — | — | CN | disclosed |
| CN-1723199-A | 1,4-disubstituted piperidine derivatives and their use as 11-beta hsd1 inhibitors | ASTRAZENECA AB (SE) | 2006-01-18 | — | — | CN | disclosed |
| EP-1085009-B1 | INDAN DERIVATIVES | NISSAN CHEMICAL IND LTD (JP) | 2004-11-10 | — | — | EP | disclosed |
| EP-0934296-B1 | CHROMAN DERIVATIVES | NISSAN CHEMICAL IND LTD (JP) | 2003-06-04 | — | — | EP | disclosed |
| US-6486178-B1 | Indane derivatives | NISSAN CHEMICAL INDUSTRIES, LTD. (JP) | 2002-11-26 | — | — | US | disclosed |
| EP-1085009-A1 | INDAN DERIVATIVES | Nissan Chemical Industries, Ltd. (JP) | 2001-03-21 | — | — | EP | disclosed |
| US-6066631-A | Chroman derivatives | NISSAN CHEMICAL INDUSTRIES, LTD. (JP) | 2000-05-23 | — | — | US | disclosed |
| WO-2000012492-A1 | BENZOXAZINE DERIVATIVES | NISSAN CHEMICAL INDUSTRIES, LTD. (JP) | 2000-03-09 | — | — | WO | disclosed |
| EP-0934296-A1 | CHROMAN DERIVATIVES | NISSAN CHEMICAL INDUSTRIES, LIMITED (JP) | 1999-08-11 | — | — | EP | disclosed |
| EP-0180188-A2 | A composition for increasing the anti-cancer activity of an anti-cancer compound | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 1986-05-07 | — | — | EP | disclosed |
| US-4565654-A | BETA-LACTAMASE ENZYME INHIBITORS | UNIVERSITY OF NOTRE DAME DU LAC (US) | 1986-01-21 | — | — | US | disclosed |
| US-4560749-A | ANTIBIOTICS, BACTERICIDES | ELI LILLY AND COMPANY (US) | 1985-12-24 | — | — | US | disclosed |
| US-4521598-A | 3-Azidocephalosporins | ELI LILLY AND COMPANY (US) | 1985-06-04 | — | — | US | disclosed |
| US-4515719-A | Azetidinone sulfinic acids from cephalosporin sulfones | ELI LILLY AND COMPANY (US) | 1985-05-07 | — | — | US | disclosed |
| EP-0136177-A2 | 3-Azidocephalosporins as intermediates and novel antibacterial agents | ELI LILLY AND COMPANY (US) | 1985-04-03 | — | — | EP | disclosed |
| EP-0132395-A1 | Improvements in or relating to the preparation of azetidinone sulfinic acids from cephalosporin sulfones | ELI LILLY AND COMPANY (US) | 1985-01-30 | — | — | EP | disclosed |
| EP-0123442-A1 | Improvements in or relating to a process for producing beta-lactam compounds | THE UNIVERSITY OF NOTRE DAME DU LAC (US) | 1984-10-31 | — | — | EP | disclosed |
| US-3960844-A | Preparation of 6-acylamino-2-methyl-2-halomethyl penams | ELI LILLY AND COMPANY (US) | 1976-06-01 | — | — | US | disclosed |
| US-3941781-A | Preparation of 3-alkylthiomethyl cephalosporins | ELI LILLY AND COMPANY (US) | 1976-03-02 | — | — | US | disclosed |