SCHEMBL249189

SCHEMBL249189

N#CCc1ccc(C#N)cc1

nearest known ligand 0.58

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
LOXL2 Q9Y4K0 2/20 0.58
CYP2A6 P11509 2/20 0.58
MAPT P10636 1/20 0.47
CYP19A1 P11511 2/20 0.47
KCNJ1 P48048 1/20 0.47
KCNH2 Q12809 1/20 0.47
ALDH1A1 P00352 1/20 0.46
CA12 O43570 1/20 0.46
CA2 P00918 1/20 0.46
CA3 P07451 1/20 0.46
CA6 P23280 1/20 0.46
CA9 Q16790 1/20 0.46
CA14 Q9ULX7 1/20 0.46
IDO1 P14902 2/20 0.45
TSHR P16473 2/20 0.43
MAOB P27338 4/20 0.42
MAOA P21397 2/20 0.42
SAE1 Q9UBE0 1/20 0.42
UBA2 Q9UBT2 1/20 0.42
HTT P42858 1/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2154504 0.86 KMT2A (0.47) LOXL2CYP2A6MAPTHTT
SCHEMBL10821186 0.80 LOXL2 (0.54) LOXL2CYP2A6MAPTCYP19A1KCNJ1
SCHEMBL16150506 0.80 LOXL2 (0.54) LOXL2CYP2A6MAPTCYP19A1KCNJ1
SCHEMBL350733 0.80 LOXL2 (0.38) LOXL2CYP2A6MAPTCA12CA2
SCHEMBL6562307 0.80 LOXL2 (0.54) LOXL2CYP2A6MAPTCYP19A1KCNJ1
SCHEMBL23137321 0.78 MMP3 (0.50) TSHRHSD17B10
SCHEMBL1004267 0.78 LOXL2 (0.64) LOXL2CYP2A6CYP19A1KCNJ1KCNH2
SCHEMBL196175 0.78 MMP3 (0.50) TSHRHSD17B10
SCHEMBL8763328 0.78 KMT2A (0.42) LOXL2MAPTALDH1A1TSHRSAE1
SCHEMBL1344068 0.78 LOXL2 (0.65) LOXL2CYP2A6CYP19A1KCNJ1KCNH2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 248 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-119143957-A Monoatomic Rh polymer catalyst and preparation method and application thereof 四川大学 2024-12-17 CN claimed
CN-117623985-A Switch-type acid-induced color change cyano stilbene compound and preparation method and application thereof 淮南师范学院 2024-03-01 CN claimed
CN-116693523-A Natural molecule rotor and preparation method and application thereof 江西广源新材料有限公司 2023-09-05 CN claimed
CN-110590701-B Benzothiazole-phenethyl cyanide compound and preparation method and application thereof 衡阳师范学院 2023-03-28 CN claimed
CN-112159381-B AIE type coumarin derivative fluorescent probe and preparation method and application thereof 南京师范大学 2022-05-03 CN claimed
CN-112159381-A AIE type coumarin derivative fluorescent probe and preparation method and application thereof 南京师范大学 2021-01-01 CN claimed
CN-110590701-A Benzothiazole-phenethyl cyanide compound and preparation method and application thereof 衡阳师范学院 2019-12-20 CN claimed
CN-109336785-A A kind of ionic-liquid catalyst and its application in synthesis 4- cyano benzyl cyanide 徐州伯利恒生物科技有限公司 2019-02-15 CN claimed
CN-109180529-A A kind of synthetic method of pesticide intermediate 4- cyano benzyl cyanide 徐州伯利恒生物科技有限公司 2019-01-11 CN claimed
EP-2382241-B1 POLYMERS FUNCTIONALIZED WITH POLYCYANO COMPOUNDS BRIDGESTONE CORP (JP) 2016-11-23 EP claimed
US-20150133628-A1 POLYAMINE AND METHOD FOR PRODUCING THEREOF RHODIA OPERATIONS (FR) 2015-05-14 US claimed
CN-102766073-B Method for synchronizing m-benzenyl trifluoride di-cyan acetonphenone JINGBO AGROCHEMICALS TECHNOLOGY CO LTD 2015-03-11 CN claimed
US-8785566-B2 Polymers functionalized with polycyano compounds BRIDGESTONE CORPORATION (JP) 2014-07-22 US claimed
US-20130123542-A1 POLYAMINE AND METHOD FOR PRODUCING THEREOF RHODIA OPERATIONS (FR) 2013-05-16 US claimed
EP-2522688-A1 POLYAMINE AND METHOD FOR PRODUCING THE SAME Rhodia Operations (FR) 2012-11-14 EP claimed
CN-102766073-A Method for synchronizing m-benzenyl trifluoride di-cyan acetonphenone YELLOW RIVER DELTA JINGBO CHEMICAL RES INST CO LTD 2012-11-07 CN claimed
CN-117623985-B Switch-type acid-induced color change cyano stilbene compound and preparation method and application thereof 淮南师范学院 2026-02-10 CN disclosed
US-20250263428-A2 AMIDE-LINKED CONJUGATE COMPOUNDS AND USES THEREOF SIMON FRASER UNIVERSITY (CA) 2025-08-21 US disclosed
EP-0017132-A1 Dyestuffs, their preparation and utilisation BASF Aktiengesellschaft (DE) 1980-10-15 EP disclosed
EP-0009788-A1 Process for the preparation of mono-chloro-acetonitrile BAYER AG (DE) 1980-04-16 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20250263428-A2 AMIDE-LINKED CONJUGATE COMPOUNDS AND USES THEREOF AADAC, DNPEP, NAALAD2 LOXL2 1788/4885CYP2A6 840/4885MAPT 1270/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.