Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KCNK3 | O14649 | 2/20 | 0.34 |
| ▸ | PTPN11 | Q06124 | 1/20 | 0.33 |
| ▸ | ITGB3 | P05106 | 4/20 | 0.32 |
| ▸ | ITGA2B | P08514 | 4/20 | 0.32 |
| ▸ | DPP4 | P27487 | 3/20 | 0.32 |
| ▸ | DPP8 | Q6V1X1 | 1/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | RAB9A | P51151 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.32 |
| ▸ | DDB1 | Q16531 | 1/20 | 0.31 |
| ▸ | CRBN | Q96SW2 | 1/20 | 0.31 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.31 |
| ▸ | GABRG2 | P18507 | 1/20 | 0.31 |
| ▸ | GABRB3 | P28472 | 1/20 | 0.31 |
| ▸ | GABRA3 | P34903 | 1/20 | 0.31 |
| ▸ | GABRA2 | P47869 | 1/20 | 0.31 |
| ▸ | GABRB2 | P47870 | 1/20 | 0.31 |
| ▸ | CTSS | P25774 | 1/20 | 0.31 |
| ▸ | HCRTR1 | O43613 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6563779 | 0.94 | KCNK3 (0.38) | KCNK3PTPN11ITGB3ITGA2BMEN1 | |
| SCHEMBL7676439 | 0.90 | HSD11B1 (0.32) | KCNK3PTPN11ITGB3ITGA2BMEN1 | |
| SCHEMBL6563364 | 0.88 | ITGB3 (0.36) | KCNK3ITGB3ITGA2BDPP4DPP8 | |
| SCHEMBL6565417 | 0.84 | PTPN11 (0.36) | KCNK3PTPN11HSD11B1DDB1CRBN | |
| SCHEMBL6563725 | 0.83 | GAA (0.33) | PTPN11MEN1KMT2ADDB1CRBN | |
| SCHEMBL6561934 | 0.82 | ACACB (0.33) | PTPN11ITGB3ITGA2BRAB9ADDB1 | |
| SCHEMBL6561984 | 0.81 | MEN1 (0.40) | KCNK3ITGB3ITGA2BMEN1RAB9A | |
| SCHEMBL6565533 | 0.80 | ACACB (0.45) | PTPN11MEN1RAB9AKMT2AHSD11B1 | |
| SCHEMBL6561843 | 0.80 | GAA (0.31) | PTPN11ITGB3ITGA2BMEN1KMT2A | |
| SCHEMBL6562329 | 0.79 | F2 (0.37) | ITGB3ITGA2BHCRTR1HCRTR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1140802-B1 | SUBSTITUTED ARYL AND HETEROARYL DERIVATIVES, THEIR PRODUCTION AND THEIR USE AS MEDICINES | BOEHRINGER INGELHEIM PHARMA (DE) | 2004-03-17 | — | — | EP | disclosed |
| US-6479524-B1 | TO PROLONG THE THROMBIN TIME | BOEHRINGER INGELHEIM PHARMA KG (DE) | 2002-11-12 | — | — | US | disclosed |