Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BTK | Q06187 | 1/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.35 |
| ▸ | ELANE | P08246 | 4/20 | 0.35 |
| ▸ | GABRP | O00591 | 2/20 | 0.34 |
| ▸ | GABRD | O14764 | 2/20 | 0.34 |
| ▸ | GABRA1 | P14867 | 2/20 | 0.34 |
| ▸ | GABRB1 | P18505 | 2/20 | 0.34 |
| ▸ | GABRG2 | P18507 | 2/20 | 0.34 |
| ▸ | GABRB3 | P28472 | 2/20 | 0.34 |
| ▸ | GABRA5 | P31644 | 2/20 | 0.34 |
| ▸ | GABRA3 | P34903 | 2/20 | 0.34 |
| ▸ | GABRA2 | P47869 | 2/20 | 0.34 |
| ▸ | GABRB2 | P47870 | 2/20 | 0.34 |
| ▸ | GABRA4 | P48169 | 2/20 | 0.34 |
| ▸ | GABRE | P78334 | 2/20 | 0.34 |
| ▸ | GABRA6 | Q16445 | 2/20 | 0.34 |
| ▸ | GABRG1 | Q8N1C3 | 2/20 | 0.34 |
| ▸ | GABRG3 | Q99928 | 2/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26964726 | 0.92 | BTK (0.38) | BTKHSD17B10KMT2AESR2ELANE | |
| SCHEMBL6974068 | 0.87 | HRH3 (0.39) | KMT2AESR2ELANETSHR | |
| SCHEMBL25647202 | 0.87 | ESR2 (0.35) | KMT2AESR2ELANE | |
| SCHEMBL5007151 | 0.84 | ELANE (0.39) | BTKHSD17B10KMT2AELANETSHR | |
| SCHEMBL7312356 | 0.83 | ESR2 (0.36) | KMT2AESR2ELANE | |
| SCHEMBL1931528 | 0.82 | ELANE (0.38) | ESR2ELANESMN1; SMN2 | |
| SCHEMBL17731339 | 0.81 | GABRP (0.38) | KMT2AESR2GABRPGABRDGABRA1 | |
| SCHEMBL165222 | 0.80 | ALDH1A1 (0.45) | KMT2AESR2TSHRSMN1; SMN2GAA | |
| SCHEMBL29148542 | 0.80 | SMN1; SMN2 (0.35) | BTKKMT2AELANESMN1; SMN2 | |
| SCHEMBL15628142 | 0.79 | HK2 (0.39) | ESR2ELANELMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-102869255-B | The novel inhibitors of GSNO reductase | 内瓦利斯治疗公司 | 2016-08-31 | — | — | CN | disclosed |
| EP-1144365-B1 | INHIBITORS OF ALPHA-4 BETA-1 MEDIATED CELL ADHESION | TANABE SEIYAKU CO (JP) | 2004-03-17 | — | — | EP | disclosed |