SCHEMBL6562692

SCHEMBL6562692

NCCCC[C@H](NS(=O)(=O)c1ccccc1)C(=O)O

nearest known ligand 0.87

Predicted protein targets (top 9)

geneUniProtsupporting neighboursconfidence
MMP9 P14780 13/20 0.87
MMP2 P08253 13/20 0.87
ADAMTS4 O75173 2/20 0.58
MMP8 P22894 2/20 0.58
MMP13 P45452 1/20 0.58
ITGB3 P05106 5/20 0.58
ITGA2B P08514 5/20 0.58
MMP12 P39900 1/20 0.52
MMP14 P50281 1/20 0.52

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6562688 1.00 MMP9 (0.87) MMP9MMP2ADAMTS4MMP8MMP13
SCHEMBL9753071 0.90 MMP9 (0.71) MMP9MMP2ADAMTS4MMP8MMP13
SCHEMBL29928063 0.89 MMP9 (0.70) MMP9MMP2ADAMTS4MMP8MMP13
SCHEMBL10585071 0.87 MMP9 (0.76) MMP9MMP2ADAMTS4MMP8MMP13
SCHEMBL8001084 0.87 MMP9 (0.76) MMP9MMP2ADAMTS4MMP8MMP13
SCHEMBL457772 0.87 MMP9 (0.76) MMP9MMP2ADAMTS4MMP8MMP13
Hydrochloric Acid SCHEMBL9087107 0.86 MMP9 (0.74) MMP9MMP2ADAMTS4MMP8MMP13
SCHEMBL7980130 0.86 MMP9 (0.67) MMP9MMP2ADAMTS4MMP8MMP13
SCHEMBL28212986 0.86 MMP9 (0.67) MMP9MMP2ADAMTS4MMP8MMP13
SCHEMBL20008635 0.86 MMP9 (0.67) MMP9MMP2ADAMTS4MMP8MMP13

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20040062773-A1 Compositions for the delivery of antigens EMISPHERE TECHNOLOGIES INC. 2004-04-01 US claimed
EP-0784469-B1 COMPOSITIONS FOR THE DELIVERY OF ANTIGENS EMISPHERE TECH INC (US) 2004-03-24 EP claimed
US-6610329-B2 Using acylated amino acid as carrier EMISPHERE TECHNOLOGIES INC. 2003-08-26 US claimed
US-20020001591-A1 Compositions for the delivery of antigens EMISPHERE TECHNOLOGIES, INC. 2002-01-03 US claimed
US-5958457-A MIXTURES OF ANTIGENS WITH ADJUVANTS AND ACYLATED AMINO ACIDS OR SALTS, POLYMERS OR SULFONATED AMINO ACIDS EMISPHERE TECHNOLOGIES, INC. (US) 1999-09-28 US claimed
EP-0784469-A4 COMPOSITIONS FOR THE DELIVERY OF ANTIGENS EMISPHERE TECH INC (US) 1999-03-24 EP claimed
EP-0784469-A1 COMPOSITIONS FOR THE DELIVERY OF ANTIGENS Emisphere Technologies, Inc. (US) 1997-07-23 EP claimed
WO-1996012474-A1 COMPOSITIONS FOR THE DELIVERY OF ANTIGENS EMISPHERE TECHNOLOGIES, INC. (US) 1996-05-02 WO claimed
US-12624109-B2 αv-integrin targeted small molecule drug conjugates TARGETTHERA LLC (US) 2026-05-12 US disclosed
US-20240376212-A1 ALPHA V-INTEGRIN TARGETED SMALL MOLECULE DRUG CONJUGATES TARGETTHERA LLC 2024-11-14 US disclosed
EP-1390053-A2 HCG FORMULATION Acevedo, Hernan F. (US) 2004-02-25 EP disclosed
WO-2002085311-A2 HCG FORMULATION ACEVEDO HERNAN F (US) 2002-10-31 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20020001591-A1 Compositions for the delivery of antigens CD47, CD74, LY96 MMP9 2979/4885MMP2 2444/4885ADAMTS4 3212/4885
US-20040062773-A1 Compositions for the delivery of antigens CD47, CD74, LY96 MMP9 2979/4885MMP2 2444/4885ADAMTS4 3212/4885
US-12624109-B2 αv-integrin targeted small molecule drug conjugates ITGA1, ITGB1, ITGA2 MMP9 1841/4885MMP2 2240/4885ADAMTS4 2648/4885
US-20240376212-A1 ALPHA V-INTEGRIN TARGETED SMALL MOLECULE DRUG CONJUGATES ITGA1, ITGAL, ITGAV MMP9 2266/4885MMP2 2229/4885ADAMTS4 3030/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.