Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TTR | P02766 | 1/20 | 0.49 |
| ▸ | HTT | P42858 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.44 |
| ▸ | MEN1 | O00255 | 2/20 | 0.44 |
| ▸ | MAPT | P10636 | 2/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
| ▸ | RAB9A | P51151 | 1/20 | 0.44 |
| ▸ | HCAR1 | Q9BXC0 | 2/20 | 0.44 |
| ▸ | CA12 | O43570 | 3/20 | 0.42 |
| ▸ | CA1 | P00915 | 3/20 | 0.42 |
| ▸ | CA2 | P00918 | 3/20 | 0.42 |
| ▸ | CA9 | Q16790 | 3/20 | 0.42 |
| ▸ | CA7 | P43166 | 2/20 | 0.42 |
| ▸ | CA14 | Q9ULX7 | 2/20 | 0.42 |
| ▸ | CA6 | P23280 | 2/20 | 0.42 |
| ▸ | CA3 | P07451 | 1/20 | 0.42 |
| ▸ | TYR | P14679 | 1/20 | 0.42 |
| ▸ | DRD1 | P21728 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6882208 | 0.81 | CA12 (0.50) | HTTSMN1; SMN2MAPTTDP1LMNA | |
| SCHEMBL6562948 | 0.81 | HSD17B1 (0.50) | HTTSMN1; SMN2MEN1MAPTKMT2A | |
| SCHEMBL6563011 | 0.79 | HSD17B1 (0.56) | HTTSMN1; SMN2MEN1MAPTKMT2A | |
| SCHEMBL8047467 | 0.76 | TPMT (0.59) | TTRSMN1; SMN2MEN1MAPTKMT2A | |
| SCHEMBL21282229 | 0.74 | SRD5A2 (0.54) | TTRHTTSMN1; SMN2MEN1KMT2A | |
| SCHEMBL6564927 | 0.74 | CA12 (0.53) | TTRHCAR1CA12CA1CA2 | |
| SCHEMBL8059881 | 0.73 | ACHE (0.52) | MAPTLMNAACHEALDH1A1CYP3A4 | |
| SCHEMBL2744380 | 0.73 | MYC (0.53) | TTRMEN1MAPTKMT2ATDP1 | |
| SCHEMBL6564894 | 0.72 | TTR (0.54) | TTRSMN1; SMN2MEN1MAPTKMT2A | |
| SCHEMBL31544755 | 0.72 | CA12 (0.47) | HTTMEN1MAPTKMT2ATDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1235777-B1 | VITAMIN D ANALOGUES | GALDERMA RES & DEV (FR) | 2004-06-16 | — | — | EP | disclosed |
| EP-1235777-A2 | VITAMIN D ANALOGUES | Galderma Research & Development, S.N.C. (FR) | 2002-09-04 | — | — | EP | disclosed |
| WO-2001038303-A2 | VITAMIN D ANALOGUES | GALDERMA RESEARCH & DEVELOPMENT, S.N.C. (FR) | 2001-05-31 | — | — | WO | disclosed |