Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD17B1 | P14061 | 1/20 | 0.50 |
| ▸ | HTT | P42858 | 1/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.47 |
| ▸ | MEN1 | O00255 | 2/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.47 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.47 |
| ▸ | LMNA | P02545 | 1/20 | 0.47 |
| ▸ | MAPT | P10636 | 1/20 | 0.47 |
| ▸ | RAB9A | P51151 | 1/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.47 |
| ▸ | GAA | P10253 | 1/20 | 0.47 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.47 |
| ▸ | CA12 | O43570 | 2/20 | 0.45 |
| ▸ | CA1 | P00915 | 2/20 | 0.45 |
| ▸ | CA2 | P00918 | 2/20 | 0.45 |
| ▸ | CA6 | P23280 | 2/20 | 0.45 |
| ▸ | CA9 | Q16790 | 2/20 | 0.45 |
| ▸ | CA3 | P07451 | 1/20 | 0.45 |
| ▸ | TYR | P14679 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14950582 | 0.85 | ALDH1A1 (0.54) | SMN1; SMN2MEN1KMT2ATDP1MAPT | |
| SCHEMBL14950602 | 0.85 | ALDH1A1 (0.54) | SMN1; SMN2MEN1KMT2ATDP1MAPT | |
| SCHEMBL68014 | 0.85 | ALDH1A1 (0.57) | SMN1; SMN2MEN1KMT2ATDP1MAPT | |
| Hydrochloric Acid SCHEMBL4352471 | 0.83 | ALDH1A1 (0.56) | SMN1; SMN2MEN1KMT2ATDP1MAPT | |
| SCHEMBL6886978 | 0.82 | CA12 (0.53) | HSD17B1HTTSMN1; SMN2MEN1KMT2A | |
| SCHEMBL6562921 | 0.81 | TTR (0.49) | HSD17B1HTTSMN1; SMN2MEN1KMT2A | |
| SCHEMBL6562840 | 0.81 | HSD17B1 (0.65) | HSD17B1HTTSMN1; SMN2KDM4EALDH1A1 | |
| SCHEMBL6563011 | 0.81 | HSD17B1 (0.56) | HSD17B1HTTSMN1; SMN2MEN1KMT2A | |
| SCHEMBL272092 | 0.80 | TTR (0.56) | KMT2AKDM4EALDH1A1GAAL3MBTL1 | |
| SCHEMBL14947557 | 0.79 | ALDH1A1 (0.49) | HSD17B1SMN1; SMN2MEN1KMT2ATDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1235777-B1 | VITAMIN D ANALOGUES | GALDERMA RES & DEV (FR) | 2004-06-16 | — | — | EP | disclosed |
| EP-1235777-A2 | VITAMIN D ANALOGUES | Galderma Research & Development, S.N.C. (FR) | 2002-09-04 | — | — | EP | disclosed |
| WO-2001038303-A2 | VITAMIN D ANALOGUES | GALDERMA RESEARCH & DEVELOPMENT, S.N.C. (FR) | 2001-05-31 | — | — | WO | disclosed |