Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | VDR | P11473 | 4/20 | 0.42 |
| ▸ | ALOX5 | P09917 | 4/20 | 0.33 |
| ▸ | MRGPRX4 | Q96LA9 | 2/20 | 0.32 |
| ▸ | FFAR1 | O14842 | 2/20 | 0.31 |
| ▸ | MAOB | P27338 | 3/20 | 0.31 |
| ▸ | PPARD | Q03181 | 1/20 | 0.30 |
| ▸ | HSD17B1 | P14061 | 1/20 | 0.30 |
| ▸ | HSD17B2 | P37059 | 1/20 | 0.30 |
| ▸ | NR4A2 | P43354 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6564905 | 0.89 | VDR (0.51) | VDRALOX5MRGPRX4FFAR1MAOB | |
| SCHEMBL6562934 | 0.89 | VDR (0.43) | VDRALOX5MRGPRX4FFAR1MAOB | |
| SCHEMBL27587218 | 0.80 | VDR (0.42) | VDRALOX5FFAR1MAOBPPARD | |
| SCHEMBL6564607 | 0.77 | VDR (0.57) | VDRMRGPRX4FFAR1MAOBNR4A2 | |
| SCHEMBL6564158 | 0.76 | VDR (0.52) | VDRFFAR1 | |
| SCHEMBL7608339 | 0.75 | VDR (0.42) | VDRALOX5MRGPRX4FFAR1MAOB | |
| SCHEMBL6562943 | 0.74 | FFAR1 (0.40) | ALOX5MRGPRX4FFAR1MAOB | |
| SCHEMBL7608336 | 0.73 | VDR (0.42) | VDRALOX5MRGPRX4FFAR1 | |
| SCHEMBL6562865 | 0.72 | VDR (0.61) | VDRFFAR1MAOBNR4A2 | |
| SCHEMBL6564937 | 0.71 | VDR (0.52) | VDRALOX5MRGPRX4MAOBPPARD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6831106-B1 | Selective activity on cell proliferation and differentiation without displaying any hypercalcaemiant nature | GALDERMA RESEARCH & DEVELOPMENT, S.N.C. (FR) | 2004-12-14 | — | — | US | claimed |