Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DAO | P14920 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.37 |
| ▸ | VDR | P11473 | 3/20 | 0.36 |
| ▸ | HPGD | P15428 | 2/20 | 0.35 |
| ▸ | HTT | P42858 | 1/20 | 0.35 |
| ▸ | GSK3B | P49841 | 3/20 | 0.34 |
| ▸ | BACE1 | P56817 | 1/20 | 0.32 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.32 |
| ▸ | POLB | P06746 | 2/20 | 0.32 |
| ▸ | IAPP | P10997 | 1/20 | 0.31 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.30 |
| ▸ | CYP4F2 | P78329 | 1/20 | 0.30 |
| ▸ | CYP4A11 | Q02928 | 1/20 | 0.30 |
| ▸ | EGFR | P00533 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6564204 | 0.80 | POLB (0.49) | MAPTVDRHPGDHTTGSK3B | |
| SCHEMBL6564816 | 0.76 | DAO (0.35) | DAOMAPTNPSR1BACE1 | |
| SCHEMBL6562975 | 0.76 | DAO (0.48) | DAOMAPTNPSR1HPGDHTT | |
| SCHEMBL7611461 | 0.75 | LTB4R (0.36) | DAOMAPTNPSR1VDREGFR | |
| SCHEMBL3280099 | 0.74 | VDR (0.53) | MAPTVDRHPGDHTTTDP1 | |
| SCHEMBL13267640 | 0.73 | MAPT (0.50) | DAOMAPTNPSR1HPGDHTT | |
| SCHEMBL6563871 | 0.73 | VDR (0.40) | VDR | |
| SCHEMBL6563862 | 0.73 | VDR (0.40) | VDR | |
| SCHEMBL6563866 | 0.73 | VDR (0.40) | VDR | |
| SCHEMBL6565145 | 0.73 | VDR (0.55) | VDR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1235824-B1 | VITAMIN D ANALOGUES | GALDERMA RES & DEV (FR) | 2004-05-19 | — | — | EP | disclosed |
| US-6706725-B1 | BIAROMATIC COMPOUNDS WHICH ARE VITAMIN D ANALOGUES | GALDERMA RESEARCH & DEVELOPMENT, S.N.C. (FR) | 2004-03-16 | — | — | US | disclosed |