Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | VDR | P11473 | 4/20 | 0.53 |
| ▸ | CYP4F2 | P78329 | 3/20 | 0.43 |
| ▸ | CYP4A11 | Q02928 | 3/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.37 |
| ▸ | RAB9A | P51151 | 3/20 | 0.37 |
| ▸ | NPC1 | O15118 | 2/20 | 0.37 |
| ▸ | HPGD | P15428 | 1/20 | 0.37 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.36 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.36 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.36 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.36 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.36 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.36 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.36 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.36 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.36 |
| ▸ | HDAC9 | Q9UKV0 | 1/20 | 0.36 |
| ▸ | HDAC5 | Q9UQL6 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 2/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6157330 | 0.86 | VDR (0.50) | VDRCYP4F2CYP4A11 | |
| SCHEMBL19090371 | 0.81 | SMN1; SMN2 (0.50) | CYP4F2CYP4A11SMN1; SMN2RAB9ANPC1 | |
| SCHEMBL6671053 | 0.81 | PRSS1 (0.52) | CYP4F2CYP4A11SMN1; SMN2RAB9ANPC1 | |
| SCHEMBL13819738 | 0.79 | KAT6A (0.50) | CYP4F2CYP4A11SMN1; SMN2RAB9ANPC1 | |
| SCHEMBL15450372 | 0.79 | ALDH1A1 (0.50) | SMN1; SMN2RAB9ANPC1HPGDMAPT | |
| SCHEMBL6756665 | 0.78 | VDR (0.47) | VDR | |
| SCHEMBL3283557 | 0.77 | LTB4R (0.41) | CYP4F2CYP4A11SMN1; SMN2RAB9ANPC1 | |
| SCHEMBL12221840 | 0.76 | CYP4F2 (0.51) | CYP4F2CYP4A11SMN1; SMN2PPARG | |
| SCHEMBL28781815 | 0.76 | CYP4F2 (0.45) | CYP4F2CYP4A11SMN1; SMN2RAB9ANPC1 | |
| SCHEMBL28268128 | 0.76 | CYP4F2 (0.45) | CYP4F2CYP4A11SMN1; SMN2RAB9ANPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7700657-B2 | Vitamin D analogs | GALDERMA RESEARCH & DEVELOPMENT (FR) | 2010-04-20 | — | — | US | disclosed |
| EP-1395538-B1 | VITAMIN D ANALOGUES | GALDERMA RES & DEV (FR) | 2009-12-30 | — | — | EP | disclosed |
| US-20040224929-A1 | Novel vitamin D analogs | GALDERMA RESEARCH & DEVELOPMENT, S.N.C. (FR) | 2004-11-11 | — | — | US | disclosed |
| EP-1395538-A1 | VITAMIN D ANALOGUES | Galderma Research & Development, S.N.C. (FR) | 2004-03-10 | — | — | EP | disclosed |
| WO-2002094754-A1 | VITAMIN D ANALOGUES | GALDERMA RESEARCH & DEVELOPMENT, S.N.C. (FR) | 2002-11-28 | — | — | WO | disclosed |