Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MRGPRX4 | Q96LA9 | 7/20 | 0.53 |
| ▸ | NR4A2 | P43354 | 5/20 | 0.50 |
| ▸ | FFAR1 | O14842 | 6/20 | 0.47 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.46 |
| ▸ | MAOB | P27338 | 1/20 | 0.45 |
| ▸ | PTGER4 | P35408 | 1/20 | 0.43 |
| ▸ | NR4A1 | P22736 | 1/20 | 0.43 |
| ▸ | NR4A3 | Q92570 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6890556 | 0.92 | NR1H2 (0.47) | MRGPRX4NR4A2FFAR1FFAR4MAOB | |
| SCHEMBL6564818 | 0.88 | MRGPRX4 (0.54) | MRGPRX4NR4A2FFAR1FFAR4NR4A1 | |
| SCHEMBL6566359 | 0.87 | MRGPRX4 (0.66) | MRGPRX4NR4A2MAOBNR4A1NR4A3 | |
| SCHEMBL6562842 | 0.86 | MRGPRX4 (0.47) | MRGPRX4NR4A2FFAR1MAOB | |
| SCHEMBL6566172 | 0.85 | MRGPRX4 (0.63) | MRGPRX4NR4A2PTGER4 | |
| SCHEMBL6562981 | 0.85 | MRGPRX4 (0.52) | MRGPRX4NR4A2MAOBPTGER4 | |
| SCHEMBL6887724 | 0.85 | MRGPRX4 (0.53) | MRGPRX4NR4A2MAOBPTGER4 | |
| SCHEMBL6883961 | 0.84 | MRGPRX4 (0.55) | MRGPRX4NR4A2MAOBPTGER4 | |
| SCHEMBL6888101 | 0.83 | MRGPRX4 (0.47) | MRGPRX4NR4A2FFAR1FFAR4MAOB | |
| SCHEMBL6882555 | 0.82 | MRGPRX4 (0.55) | MRGPRX4NR4A2FFAR1MAOBPTGER4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1235777-B1 | VITAMIN D ANALOGUES | GALDERMA RES & DEV (FR) | 2004-06-16 | — | — | EP | disclosed |
| EP-1235777-A2 | VITAMIN D ANALOGUES | Galderma Research & Development, S.N.C. (FR) | 2002-09-04 | — | — | EP | disclosed |
| WO-2001038303-A2 | VITAMIN D ANALOGUES | GALDERMA RESEARCH & DEVELOPMENT, S.N.C. (FR) | 2001-05-31 | — | — | WO | disclosed |