Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MRGPRX4 | Q96LA9 | 5/20 | 0.47 |
| ▸ | SMPD1 | P17405 | 1/20 | 0.45 |
| ▸ | NR4A2 | P43354 | 1/20 | 0.45 |
| ▸ | NR1H2 | P55055 | 1/20 | 0.45 |
| ▸ | MAOB | P27338 | 3/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | PTGER4 | P35408 | 1/20 | 0.41 |
| ▸ | NR1H4 | Q96RI1 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 3/20 | 0.41 |
| ▸ | NPC1 | O15118 | 1/20 | 0.41 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 2/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | THRB | P10828 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
| ▸ | JAK2 | O60674 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6562981 | 0.92 | MRGPRX4 (0.52) | MRGPRX4SMPD1NR4A2MAOBPTGER4 | |
| SCHEMBL6882555 | 0.91 | MRGPRX4 (0.55) | MRGPRX4SMPD1NR4A2NR1H2MAOB | |
| SCHEMBL6883961 | 0.87 | MRGPRX4 (0.55) | MRGPRX4SMPD1NR4A2MAOBSMN1; SMN2 | |
| SCHEMBL6888101 | 0.86 | MRGPRX4 (0.47) | MRGPRX4SMPD1NR4A2NR1H2MAOB | |
| SCHEMBL6890556 | 0.86 | NR1H2 (0.47) | MRGPRX4SMPD1NR4A2NR1H2MAOB | |
| SCHEMBL6566172 | 0.85 | MRGPRX4 (0.63) | MRGPRX4SMPD1NR4A2SMN1; SMN2PTGER4 | |
| SCHEMBL6887724 | 0.84 | MRGPRX4 (0.53) | MRGPRX4SMPD1NR4A2MAOBSMN1; SMN2 | |
| SCHEMBL6566359 | 0.83 | MRGPRX4 (0.66) | MRGPRX4SMPD1NR4A2MAOBNR1H4 | |
| SCHEMBL6564604 | 0.82 | MRGPRX4 (0.56) | MRGPRX4SMPD1NR4A2NR1H2MAOB | |
| SCHEMBL6564818 | 0.82 | MRGPRX4 (0.54) | MRGPRX4NR4A2NR1H4FFAR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6831106-B1 | Selective activity on cell proliferation and differentiation without displaying any hypercalcaemiant nature | GALDERMA RESEARCH & DEVELOPMENT, S.N.C. (FR) | 2004-12-14 | — | — | US | disclosed |