Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | F2 | P00734 | 16/20 | 0.41 |
| ▸ | F10 | P00742 | 2/20 | 0.37 |
| ▸ | SLC22A2 | O15244 | 1/20 | 0.37 |
| ▸ | PLG | P00747 | 1/20 | 0.37 |
| ▸ | PLAT | P00750 | 1/20 | 0.37 |
| ▸ | PROC | P04070 | 1/20 | 0.37 |
| ▸ | HPN | P05981 | 1/20 | 0.37 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.37 |
| ▸ | PRSS2 | P07478 | 1/20 | 0.37 |
| ▸ | NQO2 | P16083 | 1/20 | 0.37 |
| ▸ | PRSS3 | P35030 | 1/20 | 0.37 |
| ▸ | SLC47A2 | Q86VL8 | 1/20 | 0.37 |
| ▸ | SLC47A1 | Q96FL8 | 1/20 | 0.37 |
| ▸ | ITGB3 | P05106 | 2/20 | 0.37 |
| ▸ | ITGA2B | P08514 | 2/20 | 0.37 |
| ▸ | MMP1 | P03956 | 1/20 | 0.37 |
| ▸ | MMP9 | P14780 | 1/20 | 0.37 |
| ▸ | MMP13 | P45452 | 1/20 | 0.37 |
| ▸ | ADAM17 | P78536 | 1/20 | 0.37 |
| ▸ | TMPRSS15 | P98073 | 2/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6565355 | 0.92 | F2 (0.42) | F2F10PRSS1PRSS2NQO2 | |
| SCHEMBL6563233 | 0.88 | TMPRSS15 (0.38) | F2PRSS1PRSS2PRSS3ITGB3 | |
| SCHEMBL6563711 | 0.84 | ADAM17 (0.47) | MMP1MMP9MMP13ADAM17 | |
| SCHEMBL6562325 | 0.81 | PRSS1 (0.36) | F2F10PRSS1PRSS2PRSS3 | |
| SCHEMBL6563152 | 0.81 | F2 (0.43) | F2F10SLC22A2PLGPLAT | |
| SCHEMBL6565338 | 0.79 | F2 (0.36) | F2F10PLGPRSS1PRSS2 | |
| SCHEMBL6565497 | 0.77 | PLAU (0.48) | F2PRSS1PRSS2PRSS3MMP1 | |
| SCHEMBL6562064 | 0.76 | ADAM17 (0.43) | F2F10MMP1MMP9MMP13 | |
| SCHEMBL6564229 | 0.75 | F2 (0.43) | F2F10SLC22A2PLGPLAT | |
| SCHEMBL6563579 | 0.75 | F2 (0.37) | F2F10PRSS1PRSS2PRSS3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1140802-B1 | SUBSTITUTED ARYL AND HETEROARYL DERIVATIVES, THEIR PRODUCTION AND THEIR USE AS MEDICINES | BOEHRINGER INGELHEIM PHARMA (DE) | 2004-03-17 | — | — | EP | disclosed |
| US-6479524-B1 | TO PROLONG THE THROMBIN TIME | BOEHRINGER INGELHEIM PHARMA KG (DE) | 2002-11-12 | — | — | US | disclosed |