Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 3/20 | 0.39 |
| ▸ | TSHR | P16473 | 2/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | ACACB | O00763 | 1/20 | 0.37 |
| ▸ | PTPN11 | Q06124 | 1/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.35 |
| ▸ | ABL1 | P00519 | 1/20 | 0.35 |
| ▸ | RIN1 | Q13671 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 2/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | GLA | P06280 | 1/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.35 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.35 |
| ▸ | HTT | P42858 | 1/20 | 0.34 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.34 |
| ▸ | NPC1 | O15118 | 1/20 | 0.34 |
| ▸ | RAB9A | P51151 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6565533 | 0.92 | ACACB (0.45) | HSD11B1MEN1KMT2AACACBPTPN11 | |
| SCHEMBL6561810 | 0.91 | HSD11B1 (0.40) | HSD11B1ACACBPTPN11ABL1RIN1 | |
| SCHEMBL6563328 | 0.89 | ACACB (0.36) | HSD11B1MEN1KMT2AACACBPTPN11 | |
| SCHEMBL7674981 | 0.88 | ABL1 (0.43) | HPGDLMNAMEN1KMT2AACACB | |
| SCHEMBL7686729 | 0.86 | PTPN11 (0.43) | HPGDLMNAMEN1KMT2AACACB | |
| SCHEMBL6565336 | 0.85 | ACACB (0.34) | HPGDHSD11B1KMT2AACACBPTPN11 | |
| SCHEMBL6565093 | 0.85 | ACACB (0.35) | HPGDACACBPTPN11L3MBTL1ABL1 | |
| SCHEMBL6561973 | 0.84 | JAK1 (0.38) | HPGDKMT2AACACBPTPN11PIK3CA | |
| SCHEMBL6563220 | 0.84 | HPGD (0.44) | HPGDTSHRLMNAHSD11B1MEN1 | |
| SCHEMBL6563912 | 0.84 | ACACB (0.34) | HPGDACACBPTPN11L3MBTL1ABL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1140802-B1 | SUBSTITUTED ARYL AND HETEROARYL DERIVATIVES, THEIR PRODUCTION AND THEIR USE AS MEDICINES | BOEHRINGER INGELHEIM PHARMA (DE) | 2004-03-17 | — | — | EP | disclosed |
| US-6479524-B1 | TO PROLONG THE THROMBIN TIME | BOEHRINGER INGELHEIM PHARMA KG (DE) | 2002-11-12 | — | — | US | disclosed |