Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 3/20 | 0.59 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.59 |
| ▸ | RAB9A | P51151 | 5/20 | 0.57 |
| ▸ | NPC1 | O15118 | 3/20 | 0.57 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.57 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.57 |
| ▸ | NAMPT | P43490 | 1/20 | 0.52 |
| ▸ | MEN1 | O00255 | 2/20 | 0.50 |
| ▸ | AVPR1A | P37288 | 2/20 | 0.49 |
| ▸ | TP53 | P04637 | 1/20 | 0.49 |
| ▸ | PKM | P14618 | 1/20 | 0.49 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.49 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.49 |
| ▸ | RELA | Q04206 | 1/20 | 0.49 |
| ▸ | AVPR2 | P30518 | 1/20 | 0.48 |
| ▸ | OXTR | P30559 | 1/20 | 0.48 |
| ▸ | POLB | P06746 | 1/20 | 0.47 |
| ▸ | MAPT | P10636 | 1/20 | 0.47 |
| ▸ | TSHR | P16473 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7676415 | 0.90 | RAB9A (0.51) | HPGDALDH1A1RAB9ANPC1SMN1; SMN2 | |
| SCHEMBL6565322 | 0.83 | RAB9A (0.46) | HPGDALDH1A1RAB9ANPC1SMN1; SMN2 | |
| SCHEMBL31680509 | 0.78 | HPGD (0.90) | HPGDALDH1A1RAB9ANPC1SMN1; SMN2 | |
| SCHEMBL5783412 | 0.76 | HPGD (1.00) | HPGDALDH1A1RAB9ANPC1SMN1; SMN2 | |
| SCHEMBL31556814 | 0.76 | HPGD (1.00) | HPGDALDH1A1RAB9ANPC1SMN1; SMN2 | |
| SCHEMBL29712728 | 0.74 | SMN1; SMN2 (0.50) | HPGDALDH1A1RAB9ANPC1SMN1; SMN2 | |
| SCHEMBL27179939 | 0.72 | ALDH1A1 (0.64) | HPGDALDH1A1RAB9ANPC1SMN1; SMN2 | |
| SCHEMBL22627393 | 0.72 | HPGD (0.72) | HPGDALDH1A1RAB9ANPC1SMN1; SMN2 | |
| SCHEMBL28782860 | 0.72 | CA1 (0.56) | HPGDALDH1A1RAB9ANPC1SMN1; SMN2 | |
| SCHEMBL28801336 | 0.71 | HPGD (0.77) | HPGDALDH1A1RAB9ANPC1SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1140802-B1 | SUBSTITUTED ARYL AND HETEROARYL DERIVATIVES, THEIR PRODUCTION AND THEIR USE AS MEDICINES | BOEHRINGER INGELHEIM PHARMA (DE) | 2004-03-17 | — | — | EP | disclosed |