Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 4/20 | 0.46 |
| ▸ | NPC1 | O15118 | 3/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.44 |
| ▸ | HPGD | P15428 | 4/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.44 |
| ▸ | NAMPT | P43490 | 1/20 | 0.43 |
| ▸ | LDHA | P00338 | 1/20 | 0.42 |
| ▸ | LDHB | P07195 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | CTSL | P07711 | 1/20 | 0.41 |
| ▸ | CTSB | P07858 | 1/20 | 0.41 |
| ▸ | CTSK | P43235 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 2/20 | 0.41 |
| ▸ | AVPR1A | P37288 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | POLB | P06746 | 2/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | TP53 | P04637 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7676415 | 0.83 | RAB9A (0.51) | RAB9ANPC1SMN1; SMN2HPGDKMT2A | |
| SCHEMBL6563224 | 0.83 | HPGD (0.59) | RAB9ANPC1SMN1; SMN2HPGDKMT2A | |
| SCHEMBL6565384 | 0.83 | GRM5 (0.46) | NPC1HPGDKMT2ANAMPTMEN1 | |
| SCHEMBL7686729 | 0.82 | PTPN11 (0.43) | SMN1; SMN2HPGDKMT2ANAMPTALDH1A1 | |
| SCHEMBL7674981 | 0.82 | ABL1 (0.43) | RAB9ASMN1; SMN2HPGDKMT2ANAMPT | |
| SCHEMBL6561858 | 0.79 | GRM5 (0.47) | SMN1; SMN2HPGDKMT2ANAMPTALDH1A1 | |
| SCHEMBL6563355 | 0.79 | PTPN11 (0.47) | CTSLCTSBCTSKLMNA | |
| SCHEMBL6563002 | 0.78 | HRH3 (0.42) | NPC1HPGDNAMPTALDH1A1LMNA | |
| SCHEMBL6563511 | 0.77 | PTPN11 (0.40) | NPC1POLB | |
| SCHEMBL6563283 | 0.76 | PTPN11 (0.46) | SMN1; SMN2HPGDALDH1A1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1140802-B1 | SUBSTITUTED ARYL AND HETEROARYL DERIVATIVES, THEIR PRODUCTION AND THEIR USE AS MEDICINES | BOEHRINGER INGELHEIM PHARMA (DE) | 2004-03-17 | — | — | EP | disclosed |
| US-6479524-B1 | TO PROLONG THE THROMBIN TIME | BOEHRINGER INGELHEIM PHARMA KG (DE) | 2002-11-12 | — | — | US | disclosed |