SCHEMBL6563294 — predicted protein targets

Predicted protein targets (top 10)

	gene	UniProt	supporting neighbours	confidence
▸	L3MBTL1	Q9Y468	1/20	0.41

▸	FFAR2	O15552	1/20	0.41

▸	LMNA	P02545	1/20	0.40

▸	MAPT	P10636	1/20	0.40

▸	SMN1; SMN2	Q16637	1/20	0.40

▸	GCK	P35557	10/20	0.40

▸	KCNH2	Q12809	2/20	0.40

▸	POLB	P06746	1/20	0.40

▸	ROCK2	O75116	1/20	0.39

▸	ROCK1	Q13464	1/20	0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compound	similarity	top predicted	shared targets
SCHEMBL6563666	0.93	FFAR2 (0.43)	FFAR2GCKKCNH2ROCK2ROCK1
SCHEMBL6560881	0.90	FFAR2 (0.52)	FFAR2GCK
SCHEMBL2646714	0.86	L3MBTL1 (0.58)	L3MBTL1FFAR2LMNAMAPTSMN1; SMN2
SCHEMBL14435743	0.85	MAPT (0.59)	LMNAMAPTSMN1; SMN2KCNH2POLB
SCHEMBL2646718	0.85	MAPT (0.59)	LMNAMAPTSMN1; SMN2KCNH2POLB
SCHEMBL6596857	0.85	GCK (0.51)	FFAR2GCKPOLB
SCHEMBL6561909	0.82	GCK (0.61)	GCKKCNH2
SCHEMBL6563774	0.82	FFAR2 (0.56)	FFAR2GCKKCNH2
SCHEMBL6563810	0.82	KCNH2 (0.45)	FFAR2GCKKCNH2
SCHEMBL2658530	0.82	L3MBTL1 (0.46)	L3MBTL1FFAR2SMN1; SMN2GCKKCNH2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

Patent	Title	Assignee	Published	Priority	Filing	Country	Status
EP-1169312-B1	GLUCOKINASE ACTIVATORS	HOFFMANN LA ROCHE (CH)	2004-10-06	—	—	EP	claimed