Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FFAR2 | O15552 | 1/20 | 0.48 |
| ▸ | KCNH2 | Q12809 | 3/20 | 0.44 |
| ▸ | GCK | P35557 | 8/20 | 0.43 |
| ▸ | EPHX2 | P34913 | 2/20 | 0.39 |
| ▸ | KCNQ2 | O43526 | 1/20 | 0.39 |
| ▸ | METAP2 | P50579 | 1/20 | 0.39 |
| ▸ | GLS | O94925 | 2/20 | 0.39 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.38 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6563797 | 0.88 | FFAR2 (0.62) | FFAR2KCNH2GCK | |
| SCHEMBL6561897 | 0.87 | FFAR2 (0.48) | FFAR2KCNH2GCKKCNQ2 | |
| SCHEMBL2656985 | 0.83 | FFAR2 (0.70) | FFAR2KCNH2GCKEPHX2MEN1 | |
| SCHEMBL2646346 | 0.83 | FFAR2 (0.70) | FFAR2KCNH2GCKEPHX2MEN1 | |
| SCHEMBL6561977 | 0.81 | GCK (0.51) | FFAR2KCNH2GCK | |
| SCHEMBL6562292 | 0.81 | KCNH2 (0.63) | FFAR2KCNH2GCK | |
| SCHEMBL6563227 | 0.81 | KCNH2 (0.49) | FFAR2KCNH2GCKEPHX1 | |
| SCHEMBL27548008 | 0.80 | FFAR2 (0.46) | FFAR2KCNH2GCKROCK2 | |
| SCHEMBL13609600 | 0.79 | KCNH2 (0.48) | FFAR2KCNH2GCKMETAP2GLS | |
| SCHEMBL2658530 | 0.78 | L3MBTL1 (0.46) | FFAR2KCNH2GCKROCK2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1169312-B1 | GLUCOKINASE ACTIVATORS | HOFFMANN LA ROCHE (CH) | 2004-10-06 | — | — | EP | claimed |